Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6709007 | 0.98 | MAPT (0.56) | MAPTTDP1KMT2AMAPK1MEN1 | |
| Formaldehyde SCHEMBL4564999 | 0.96 | MAPT (0.54) | MAPTTDP1KMT2AMAPK1MEN1 | |
| SCHEMBL4126030 | 0.93 | CA12 (0.51) | MAPTTDP1KMT2AMAPK1MEN1 | |
| SCHEMBL20643854 | 0.88 | TDP1 (0.64) | MAPTTDP1KMT2AMAPK1MEN1 | |
| SCHEMBL9744775 | 0.83 | TDP1 (0.62) | MAPTTDP1KMT2AMAPK1MEN1 | |
| SCHEMBL10877229 | 0.82 | HSD17B3 (0.62) | TDP1KDM4ECYP3A4L3MBTL1SIGMAR1 | |
| SCHEMBL19399103 | 0.82 | KMT2A (0.60) | MAPTTDP1KMT2AMEN1CES1 | |
| SCHEMBL27937324 | 0.80 | MAPT (0.54) | MAPTTDP1KMT2AMAPK1MEN1 | |
| SCHEMBL10523300 | 0.80 | NR4A2 (0.59) | MAPTTDP1KMT2AMAPK1MEN1 | |
| SCHEMBL16404442 | 0.80 | ALDH1A1 (0.53) | MAPTTDP1KMT2AMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110050365-B | Improved secondary lithium ion battery and lithium capacitor electrode compositions | 汉高股份有限及两合公司 | 2023-04-28 | — | — | CN | claimed |
| CN-115677512-A | Method for synthesizing lercanidipine intermediate N-methyl-3,3-diphenylpropylamine hydrochloride | 大连万福制药有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-112359028-B | Biosynthesis method of tomoxetine intermediate and carbonyl reductase | 江苏阿尔法药业股份有限公司 | 2022-05-31 | — | — | CN | claimed |
| CN-112359028-A | Biosynthesis method of tomoxetine intermediate and carbonyl reductase | 江苏阿尔法药业有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-111186180-A | High-film-separation VCM color-coated sheet for furniture | 苏州兴禾源复合材料有限公司 | 2020-05-22 | — | — | CN | claimed |
| CN-108998779-B | Chemical plating solution and environment-friendly alloy surface autocatalytic treatment method | 绵阳高新区天力机械有限责任公司 | 2020-03-10 | — | — | CN | claimed |
| CN-109772113-A | A kind of deodorant of petrochemical industry sour gas | 吕秀梅 | 2019-05-21 | — | — | CN | claimed |
| CN-109228597-A | A kind of anti-rotten, pressure resistant type religion toy composite board | 钱学华 | 2019-01-18 | — | — | CN | claimed |
| CN-108998779-A | A kind of chemical plating fluid and environment-friendly type alloy surface self-catalysis processing method | 四川鑫元瑞科技有限公司 | 2018-12-14 | — | — | CN | claimed |
| CN-108927868-A | A kind of nontoxic non-stimulated religion toy timber preservative | 钱学华 | 2018-12-04 | — | — | CN | claimed |
| US-7579484-B2 | Preparation of 3-methylamino-1-phenyl-1-propanone or 3-methylamino-1-(2-thienyl)-1-propanone; chemical intermediates to central nervous system drugs such as fluoxetine, tomoxetine | MERCK PATENT GMBH (DE) | 2009-08-25 | — | — | US | claimed |
| CN-1293039-C | Preparation of [(S)-(-)-alpha-methylamino phenylketone]2.(2R,3R)-tartaric acid derivative | SHANGHAI INST OF MEDICINE INDU (CN) | 2007-01-03 | — | — | CN | claimed |
| US-20060122405-A1 | Method for the production of monoalkylamino ketones | MERCK PATENT GMBH (DE) | 2006-06-08 | — | — | US | claimed |
| US-6984738-B2 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU | 2006-01-10 | — | — | US | claimed |
| EP-1532101-A1 | METHOD FOR THE PRODUCTION OF MONOALKYLAMINO KETONES | MERCK PATENT GmbH (DE) | 2005-05-25 | — | — | EP | claimed |
| CN-1583714-A | Preparation of [(S)-(-)-alpha-methylamino phenylketone]2.(2R,3R)-tartaric acid derivative | SHANGHAI MEDICAL INDUSTRY ACAD (CN) | 2005-02-23 | — | — | CN | claimed |
| WO-2004020391-A1 | METHOD FOR THE PRODUCTION OF MONOALKYLAMINO KETONES | MERCK PATENT GMBH (DE) | 2004-03-11 | — | — | WO | claimed |
| EP-0461113-A1 | TANNIN MANNICH ADDUCTS FOR IMPROVING CORROSION RESISTANCE OF METALS | HENKEL CORPORATION (US) | 1991-12-18 | — | — | EP | claimed |
| US-4944812-A | Tannin mannich adducts for improving corrosion resistance of metals | HENKEL CORPORATION (US) | 1990-07-31 | — | — | US | claimed |
| WO-1990005794-A1 | TANNIN MANNICH ADDUCTS FOR IMPROVING CORROSION RESISTANCE OF METALS | HENKEL CORPORATION (US) | 1990-05-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122405-A1 | Method for the production of monoalkylamino ketones | BCKDK, AKR7A2, AKR1C3 | MAPT 2957/4885TDP1 4340/4885KMT2A 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.