Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907907 | 0.84 | CA1 (0.52) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL214386 | 0.82 | GABRA1 (0.46) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL11989394 | 0.82 | GABRA1 (0.40) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL1973265 | 0.80 | CA1 (0.48) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL17281733 | 0.78 | CA1 (0.56) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL4625321 | 0.77 | GABRA1 (0.46) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL70105 | 0.77 | CA1 (0.45) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL17293890 | 0.76 | ERN1 (0.42) | GABRA1GABRB1CA1CA2LMNA | |
| SCHEMBL29484753 | 0.76 | CA1 (0.43) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL11061545 | 0.75 | CA1 (0.59) | GABRA1GABRB1CA1CA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2949638-B1 | METHOD FOR THE PREPARATION OF 2,2 -BIPHENOLS USING SELENIUM DIOXIDE | EVONIK DEGUSSA GMBH (DE) | 2017-11-08 | — | — | EP | disclosed |
| EP-2421875-B1 | HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES | INVISTA TECHNOLOGIES SARL (CH) | 2017-08-23 | — | — | EP | disclosed |
| US-9517986-B2 | Process for preparing 2,2′-biphenols using selenium dioxide | EVONIK DEGUSSA GMBH (DE) | 2016-12-13 | — | — | US | disclosed |
| US-9517986-B2 | Process for preparing 2,2′-biphenols using selenium dioxide | EVONIK DEGUSSA GMBH (DE) | 2016-12-13 | — | — | US | disclosed |
| EP-2421876-B1 | HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES | INVISTA Technologies S à r l (CH) | 2016-07-27 | — | — | EP | disclosed |
| EP-2771347-B1 | METHODS FOR PRODUCING ORGANODIPHOSPHITES FROM PHOSPHOROCHLORIDITES CHARACTERIZED BY MEASURING SIDE-PRODUCT LEVELS TO DETERMINE FURTHER ADDITIONS | INVISTA Technologies S à r l (CH) | 2016-07-27 | — | — | EP | disclosed |
| EP-2395010-B1 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA Technologies S à r l (CH) | 2016-07-13 | — | — | EP | disclosed |
| US-9221852-B2 | Method for making organodiphosphites from phosphorochloridites characterized by measuring side-product levels to determine further additions | INVISTA NORTH AMERICA S.A.R.L. (US) | 2015-12-29 | — | — | US | disclosed |
| US-9221852-B2 | Method for making organodiphosphites from phosphorochloridites characterized by measuring side-product levels to determine further additions | INVISTA NORTH AMERICA S.A.R.L. (US) | 2015-12-29 | — | — | US | disclosed |
| EP-2949638-A1 | METHOD FOR THE PREPARATION OF 2,2 -BIPHENOLS USING SELENIUM DIOXIDE | Evonik Degussa GmbH (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-7629484-B2 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA NORTH AMERICA S.A.R.L. (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629484-B2 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA NORTH AMERICA S.A.R.L. (US) | 2009-12-08 | — | — | US | disclosed |
| EP-1905511-A2 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA Technologies S.à.r.l. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007109005-A2 | METHOD FOR THE PURIFICATION OF TRIORGANOPHOSPHITES BY TREATMENT WITH A BASIC ADDITIVE | INVISTA TECHNOLOGIES S.A R.L. (CH) | 2007-09-27 | — | — | WO | disclosed |
| US-20070219386-A1 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA NORTH AMERICA S.A R.L. (US) | 2007-09-20 | — | — | US | disclosed |
| US-20070219386-A1 | Method for the purification of triorganophosphites by treatment with a basic additive | INVISTA NORTH AMERICA S.A R.L. (US) | 2007-09-20 | — | — | US | disclosed |
| US-6924345-B2 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA NORTH AMERICA S.A R.L. (US) | 2005-08-02 | — | — | US | disclosed |
| US-20040054105-A1 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INV NYLON CHEMICALS AMERICAS, LLC | 2004-03-18 | — | — | US | disclosed |
| US-6660876-B2 | Ethylenically unsaturated, phosphorus-containing, bidentate ligands | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-12-09 | — | — | US | disclosed |
| US-20030144440-A1 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INV NYLON CHEMICALS AMERICAS, LLC | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219386-A1 | Method for the purification of triorganophosphites by treatment with a basic additive | HRH3, PHOSPHO1, HRH4 | GABRA1 4302/4885GABRB1 4365/4885CA1 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.