Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244520 | 0.84 | GABRA1 (0.48) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL4625321 | 0.82 | GABRA1 (0.46) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL993799 | 0.82 | GABRA1 (0.52) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL29484753 | 0.80 | CA1 (0.43) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL1244523 | 0.79 | TSHR (0.42) | GABRA1GABRB1CA1CA2HPGD | |
| SCHEMBL4907907 | 0.79 | CA1 (0.52) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL4613445 | 0.78 | GABRA1 (0.54) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL1973265 | 0.76 | CA1 (0.48) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL1242990 | 0.75 | GABRA1 (0.41) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL1242976 | 0.75 | CA2 (0.42) | GABRA1GABRB1CA1CA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9517986-B2 | Process for preparing 2,2′-biphenols using selenium dioxide | EVONIK DEGUSSA GMBH (DE) | 2016-12-13 | — | — | US | claimed |
| US-20150336865-A1 | PROCESS FOR PREPARING 2,2'-BIPHENOLS USING SELENIUM DIOXIDE | EVONIK DEGUSSA GMBH (DE) | 2015-11-26 | — | — | US | claimed |
| EP-2658651-B1 | NICKEL COMPOSITIONS FOR PREPARING NICKEL METAL AND NICKEL COMPLEXES | INVISTA TEXTILES UK LTD (GB) | 2018-10-17 | — | — | EP | disclosed |
| US-9981257-B2 | Metal-ligand catalyst formation | INVISTA NORTH AMERICA S.A.R.L. (US) | 2018-05-29 | — | — | US | disclosed |
| EP-2229353-B1 | HYDROCYANATION OF PENTENENITRILES | INVISTA TEXTILES (U K ) LTD (GB) | 2018-01-03 | — | — | EP | disclosed |
| EP-2949638-B1 | METHOD FOR THE PREPARATION OF 2,2 -BIPHENOLS USING SELENIUM DIOXIDE | EVONIK DEGUSSA GMBH (DE) | 2017-11-08 | — | — | EP | disclosed |
| EP-2614070-B1 | NICKEL COMPOSITIONS FOR PREPARING NICKEL METAL AND NICKEL COMPLEXES | INVISTA TECHNOLOGIES SARL (CH) | 2017-07-26 | — | — | EP | disclosed |
| US-9687836-B2 | Nickel form for preparation of catalytic nickel-ligand complexes | INVISTA NORTH AMERICA S.A R.L. (US) | 2017-06-27 | — | — | US | disclosed |
| US-9517986-B2 | Process for preparing 2,2′-biphenols using selenium dioxide | EVONIK DEGUSSA GMBH (DE) | 2016-12-13 | — | — | US | disclosed |
| EP-2512673-B1 | NICKEL METAL COMPOSITIONS AND NICKEL COMPLEXES DERIVED FROM BASIC NICKEL CARBONATES | INVISTA Technologies S à r l (CH) | 2016-09-28 | — | — | EP | disclosed |
| US-9371346-B2 | Preparing a nickel phosphorus ligand complex | INVISTA NORTH AMERICA S.A.R.L. (US) | 2016-06-21 | — | — | US | disclosed |
| US-6984604-B2 | Supported bis(phosphorus) ligands and their use in the catalysis | INVISTA NORTH AMERICA S.A.R.L. (US) | 2006-01-10 | — | — | US | disclosed |
| US-6924345-B2 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA NORTH AMERICA S.A R.L. (US) | 2005-08-02 | — | — | US | disclosed |
| EP-1448298-A2 | POLYMERIC PHOSPHORUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, UNSATURATED NITRILE ISOMERIZATION AND HYDROFORMYLATION REACTIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-08-25 | — | — | EP | disclosed |
| US-20040054105-A1 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INV NYLON CHEMICALS AMERICAS, LLC | 2004-03-18 | — | — | US | disclosed |
| US-6660876-B2 | Ethylenically unsaturated, phosphorus-containing, bidentate ligands | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-12-09 | — | — | US | disclosed |
| US-20030153691-A1 | Supported bis(phosphorus) ligands and their use in the catalysis | INVISTA NORTH AMERICA S.A.R.L. | 2003-08-14 | — | — | US | disclosed |
| US-20030144440-A1 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INV NYLON CHEMICALS AMERICAS, LLC | 2003-07-31 | — | — | US | disclosed |
| WO-2003045552-A2 | POLYMERIC PHOSPHORUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, UNSATURATED NITRILE ISOMERIZATION AND HYDROFORMYLATION REACTIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-06-05 | — | — | WO | disclosed |
| US-20030100802-A1 | Process for preparing 3,3',5,5',6,6'-hexaalkyl-2,2'-biphenols,3,3',4,4',5,5'-hexaalkyl-2,2'-biphenols and 3,3',4,4',5,5',6,6'-octaalkyl-2,2'-biphenols | SHAPIRO RAFAEL (US) | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100802-A1 | Process for preparing 3,3',5,5',6,6'-hexaalkyl-2,2'-biphenols,3,3',4,4',5,5'-hexaalkyl-2,2'-biphenols and 3,3',4,4',5,5',6,6'-octaalkyl-2,2'-biphenols | CYP4B1, UGT1A4, CYP4X1 | GABRA1 1613/4885GABRB1 1560/4885CA1 2816/4885 |
| US-20150336865-A1 | PROCESS FOR PREPARING 2,2'-BIPHENOLS USING SELENIUM DIOXIDE | SELENOI, PLK1, BPGM | GABRA1 1551/4885GABRB1 1382/4885CA1 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.