Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724255 | 0.94 | TDP1 (0.46) | TSHRTDP1HSD17B10LMNAKMT2A | |
| SCHEMBL722524 | 0.91 | TSHR (0.54) | TSHRTDP1HSD17B10LMNAKMT2A | |
| SCHEMBL18832126 | 0.81 | HSD17B10 (0.45) | TSHRTDP1HSD17B10LMNAKMT2A | |
| SCHEMBL724257 | 0.81 | TSHR (0.48) | TSHRTDP1HSD17B10LMNAKMT2A | |
| SCHEMBL9938116 | 0.80 | TSHR (0.39) | TSHRTDP1HSD17B10LMNAKMT2A | |
| SCHEMBL2452970 | 0.79 | CES2 (0.44) | TSHRTDP1HSD17B10KMT2AALDH1A1 | |
| SCHEMBL18832140 | 0.79 | HSD17B10 (0.53) | TSHRTDP1HSD17B10KMT2AALDH1A1 | |
| SCHEMBL722430 | 0.78 | TSHR (0.68) | TSHRTDP1HSD17B10LMNAKMT2A | |
| SCHEMBL18832128 | 0.78 | HSD17B10 (0.57) | TSHRTDP1HSD17B10KMT2AALDH1A1 | |
| SCHEMBL18832148 | 0.78 | HSD17B10 (0.57) | TSHRTDP1HSD17B10KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081712-A1 | PROCESS FOR THE PREPARATION OF HYDROXYCARBOXYLIC ACID COMPOUND OR SALT THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-21 | — | — | WO | disclosed |