Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938112 | 0.80 | TSHR (0.47) | TSHRALDH1A1HPGDTDP1LMNA | |
| SCHEMBL9936987 | 0.73 | TSHR (0.44) | TSHRHSD17B10CES2CES1 | |
| SCHEMBL724255 | 0.73 | TDP1 (0.46) | TSHRALDH1A1HPGDTDP1LMNA | |
| SCHEMBL28442996 | 0.71 | CES2 (0.61) | TSHRALDH1A1CES2CES1 | |
| SCHEMBL722524 | 0.70 | TSHR (0.54) | TSHRALDH1A1HPGDTDP1LMNA | |
| SCHEMBL12164666 | 0.70 | ALDH1A1 (0.45) | TSHRALDH1A1HPGDTDP1LMNA | |
| SCHEMBL18348903 | 0.68 | — | — | |
| SCHEMBL200623 | 0.68 | — | — | |
| SCHEMBL13251728 | 0.68 | — | — | |
| SCHEMBL21114377 | 0.68 | CES1 (0.65) | TSHRALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081712-A1 | PROCESS FOR THE PREPARATION OF HYDROXYCARBOXYLIC ACID COMPOUND OR SALT THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-21 | — | — | WO | disclosed |