SCHEMBL722524

SCHEMBL722524

CCSCCC(=O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
OR51E2 Q9H255 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPK1 P28482 1/20 0.42
SLC13A3 Q8WWT9 1/20 0.42
EGLN1 Q9GZT9 1/20 0.42
LMNA P02545 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
HAO1 Q9UJM8 1/20 0.34
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
FFAR3 O14843 3/20 0.32
HDAC3 O15379 2/20 0.32
HDAC1 Q13547 2/20 0.32
HDAC2 Q92769 2/20 0.32
HDAC8 Q9BY41 2/20 0.32
GMNN O75496 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9938112 0.91 TSHR (0.47) TSHROR51E2HSD17B10MAPK1SLC13A3
SCHEMBL722430 0.86 TSHR (0.68) TSHROR51E2HSD17B10MAPK1SLC13A3
SCHEMBL722984 0.84 TSHR (0.59) TSHROR51E2HSD17B10MAPK1SLC13A3
SCHEMBL724255 0.83 TDP1 (0.46) TSHROR51E2HSD17B10MAPK1SLC13A3
SCHEMBL9938114 0.80 CES2 (0.44) TSHROR51E2HSD17B10KMT2ATDP1
SCHEMBL18832126 0.79 HSD17B10 (0.45) TSHRHSD17B10LMNAKMT2ATDP1
SCHEMBL1196750 0.79
SCHEMBL18832140 0.78 HSD17B10 (0.53) TSHRHSD17B10KMT2ATDP1ALDH1A1
SCHEMBL9936985 0.78 TSHR (0.52) TSHROR51E2HSD17B10MAPK1SLC13A3
SCHEMBL4276502 0.76 TSHR (0.50) TSHRHSD17B10LMNAKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795511-B Oxidase, polynucleotide encoding the same, and use thereof 住友化学株式会社 2020-02-11 CN disclosed
CN-106661571-B Oxidase, polynucleotide encoding the same, and use thereof 住友化学株式会社 2019-12-20 CN disclosed
EP-3168301-B1 OXIDASE, POLYNUCLEOTIDE ENCODING SAME, AND USE OF THESE SUMITOMO CHEMICAL CO (JP) 2019-11-20 EP disclosed
US-10364448-B2 Method for producing L-α-amino acid compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-30 US disclosed
US-10351829-B2 Oxidase, polynucleotide that codes for same, and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-16 US disclosed
US-20170191097-A1 OXIDASE, POLYNUCLEOTIDE ENCODING SAME, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-06 US disclosed
US-20170159029-A1 OXIDASE, POLYNUCLEOTIDE THAT CODES FOR SAME, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-08 US disclosed
EP-3168302-A1 OXIDASE, POLYNUCLEOTIDE THAT CODES FOR SAME, AND USES FOR BOTH Sumitomo Chemical Company, Limited (JP) 2017-05-17 EP disclosed
EP-3168301-A1 OXIDASE, POLYNUCLEOTIDE ENCODING SAME, AND USE OF THESE Sumitomo Chemical Company, Limited (JP) 2017-05-17 EP disclosed
EP-2550251-B1 PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF SUMITOMO CHEMICAL CO (JP) 2015-04-29 EP disclosed
US-20130137897-A1 PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-30 US disclosed
EP-2550251-A1 PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF Sumitomo Chemical Company, Limited (JP) 2013-01-30 EP disclosed
US-20130012737-A1 PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-10 US disclosed
WO-2012026620-A1 PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 WO disclosed
WO-2012026619-A1 PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 WO disclosed
WO-2011118849-A1 PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-29 WO disclosed
EP-0206460-B1 L-PHENYLALANINE DEHYDROGENASE AND USE THEREOF SAGAMI CHEMICAL RESEARCH CENTER (JP) 1993-08-11 EP disclosed
EP-0513872-A1 L-phenylalanine dehydrogenase and use thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-11-19 EP disclosed
US-4849345-A L-phenylalanine dehydrogenase and use thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-07-18 US disclosed
EP-0206460-A2 L-phenylalanine dehydrogenase and use thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351829-B2 Oxidase, polynucleotide that codes for same, and use thereof DAO, PNPO, HAO1 TSHR 4623/4885OR51E2 1445/4885HSD17B10 774/4885
US-20130137897-A1 PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND HPD, STS, HAO2 TSHR 4553/4885OR51E2 815/4885HSD17B10 76/4885
US-20130012737-A1 PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF CBS, ASS1, TST TSHR 2658/4885OR51E2 3742/4885HSD17B10 1711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.