Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042337 | 0.80 | NPC1 (0.37) | — | |
| SCHEMBL9939587 | 0.77 | ATR (0.38) | — | |
| SCHEMBL23461777 | 0.77 | KDM4E (0.37) | — | |
| SCHEMBL16208226 | 0.75 | NPC1 (0.33) | — | |
| SCHEMBL3708385 | 0.75 | KCNQ3 (0.33) | ERN1 | |
| SCHEMBL21773959 | 0.74 | ERN1 (0.47) | PTGDR2ERN1 | |
| SCHEMBL19616132 | 0.73 | ASPH (0.41) | — | |
| SCHEMBL4597010 | 0.72 | GRIA1 (0.37) | ERN1TRIM24TRIM33 | |
| SCHEMBL7993654 | 0.71 | LMNA (0.41) | ERN1TRIM24TRIM33 | |
| SCHEMBL26617759 | 0.71 | ERN1 (0.42) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651899-A2 | SUBSTITUTED 6,6-FUSED NITROGENOUS HETEROCYCLIC COMPOUNDS AND USES THEREOF | F.HOFFMANN-LA ROCHE AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080284-A2 | SUBSTITUTED 6,6-FUSED NITROGENOUS HETEROCYCLIC COMPOUNDS AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-21 | — | — | WO | disclosed |