Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22095295 | 0.82 | KLK5 (0.48) | GABRA1GABRB2ALDH1A1MAPTMEN1 | |
| SCHEMBL7242960 | 0.82 | KLK5 (0.48) | GABRA1GABRB2ALDH1A1MAPTMEN1 | |
| SCHEMBL10064081 | 0.79 | PTGS2 (0.37) | GABRA1GABRB2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL5116383 | 0.76 | PPARG (0.48) | GABRA1GABRB2ESR1ESR2TTR | |
| SCHEMBL10064139 | 0.75 | DRD3 (0.35) | GABRA1GABRB2ESR2ALDH1A1MAPT | |
| SCHEMBL14038361 | 0.75 | ESR2 (0.41) | ESR1ESR2TTRMIFALDH1A1 | |
| SCHEMBL14007732 | 0.74 | ESR2 (0.43) | ESR1ESR2TTRMIFALDH1A1 | |
| SCHEMBL7212449 | 0.73 | ESR2 (0.42) | GABRA1GABRB2ESR2ALDH1A1CYP3A4 | |
| SCHEMBL9734501 | 0.73 | KDM4E (0.50) | ALDH1A1MAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL13161546 | 0.72 | DRD3 (0.34) | ESR2ALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651886-B1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | ORÉAL L (FR) | 2015-03-04 | — | — | EP | disclosed |
| EP-2651886-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'Oréal (FR) | 2013-10-23 | — | — | EP | disclosed |
| CN-103282348-A | Method for depigmenting keratin materials using resorcinol derivatives | OREAL | 2013-09-04 | — | — | CN | disclosed |
| WO-2012079938-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |