SCHEMBL993865

SCHEMBL993865

COC(=O)C1C=CC(N)C1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.37
ANPEP P15144 1/20 0.37
CHRNB2 P17787 2/20 0.34
CHRNA4 P43681 2/20 0.34
ABAT P80404 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2208895 1.00 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
SCHEMBL19337855 1.00 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
SCHEMBL14480001 1.00 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
SCHEMBL993866 1.00 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
Hydrochloric Acid SCHEMBL6079312 0.98 MMP2 (0.36) MMP2ANPEPCHRNB2CHRNA4ABAT
Hydrochloric Acid SCHEMBL4093850 0.98 MMP2 (0.36) MMP2ANPEPCHRNB2CHRNA4ABAT
Hydrochloric Acid SCHEMBL6081955 0.98 MMP2 (0.36) MMP2ANPEPCHRNB2CHRNA4ABAT
Hydrochloric Acid SCHEMBL4426352 0.98 MMP2 (0.36) MMP2ANPEPCHRNB2CHRNA4ABAT
Sulfuric Acid SCHEMBL6078882 0.93 MMP2 (0.33) MMP2ANPEPCHRNB2CHRNA4ABAT
Sulfuric Acid SCHEMBL6078890 0.93 MMP2 (0.33) MMP2ANPEPCHRNB2CHRNA4ABAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079801-A Synthesis method and analysis method of (1S, 4R) -4-amino-2-cyclopentene-1-carboxylic acid methyl ester tartrate 2026-05-26 CN claimed
CN-122079801-A Synthesis method and analysis method of (1S, 4R) -4-amino-2-cyclopentene-1-carboxylic acid methyl ester tartrate 2026-05-26 CN disclosed
CN-122079801-A Synthesis method and analysis method of (1S, 4R) -4-amino-2-cyclopentene-1-carboxylic acid methyl ester tartrate 2026-05-26 CN disclosed
CN-119431264-A 3-Phenyl isoxazoline-5-formamide oxime ester compound and application thereof 沈阳万菱生物技术有限公司 2025-02-14 CN disclosed
EP-3892278-B1 CYCLOALKANE-1,3-DIAMINE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2024-02-28 EP disclosed
WO-2023161874-A1 CYTOTOXICITY TARGETING CHIMERAS FOR C-C CHEMOKINE RECEPTOR 2-EXPRESSING CELLS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2023-08-31 WO disclosed
CN-112341350-A Method for treating by-product after enzymatic resolution of gamma-lactam 江苏威奇达药业有限公司 2021-02-09 CN disclosed
CN-111072547-A Chemical preparation method of 2-azabicyclo [2.2.1] hept-5-ene-3-ketone with optical activity 南京正济医药研究有限公司 2020-04-28 CN disclosed
US-8906911-B2 Chemokine receptor antagonists ABBVIE INC. (US) 2014-12-09 US disclosed
EP-2448916-B1 PRODUCTION OF TRANS-4-AMINOCYCLOPENT-2-ENE-1-CARBOXYLIC ACID DERIVATIVES REDDYS LAB LTD DR (IN) 2014-09-03 EP disclosed
WO-2011003061-A2 PRODUCTION OF TRAN S-4-AMINOCYCLOPENT-2-ENE-1-CARBOXYLIC ACID DERIVATIVES DR. REDDY'S LABORATORIES LTD. (IN) 2011-01-06 WO disclosed
US-7038059-B2 Process for preparation of 4-n-substituted amino-2-aza-1-oxabicyclo[3.3.0] oct-2-ene-6-carboxylic acid esters and process for preparation of their intermediates KURARAY CO., LTD. (JP) 2006-05-02 US disclosed
US-20040121482-A1 Process for preparation of 4-n-substituted amino-2-aza-1-oxabicyclo[3.3.0] oct-2-ene-6-carboxylic acid esters and process for preparation of their intermediates KURARAY CO., LTD. (JP) 2004-06-24 US disclosed
EP-1334969-A1 PROCESS FOR PREPARATION OF 4-N-SUBSTITUTED AMINO-2-AZA-1-OXABICYCLO 3.3.0]OCT-2-ENE-6-CARBOXYLIC ACID ESTERS AND PROCESS FOR PREPARATION OF THEIR INTERMEDIATES KURARAY CO., LTD. (JP) 2003-08-13 EP disclosed
US-6495711-B2 1-(TERT-BUTOXYCARBONYLAMINO)-4-METHOXYCARBONYL-CYCLOPENT-2-ENE STARTING BY REACTING 2-AZABICYCLO(2.2.1)HEPT-5-EN-3-ONE WITH AN ALCOHOL AND NONAQUEOUS ACID; CHEMICAL INTERMEDIATES TO ANTIVIRAL AGENTS AGAINST INFLUENZA VIRUS BIOCRYST PHARMACEUTICALS INC. 2002-12-17 US disclosed
EP-1206443-A2 PROCESS FOR PREPARING (-)-(1S,4R) N-PROTECTED 4-AMINO-2-CYCLOPENTENE-1-CARBOXYLATE ESTERS BIOCRYST PHARMACEUTICALS, INC. (US) 2002-05-22 EP disclosed
US-20020052524-A1 Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters BIOCRYST PHARMACEUTICALS, INC. 2002-05-02 US disclosed
EP-1165829-A1 THE PREPARATION OF (trans)-4-AMINO-2-CYCLOPENTENE-1-CARBOXYLIC ACID DERIVATIVES Chirotech Technology Limited (GB) 2002-01-02 EP disclosed
WO-2001001569-A2 PROCESS FOR PREPARING (-)-(1S,4R) N-PROTECTED 4-AMINO-2-CYCLOPENTENE-1-CARBOXYLATE ESTERS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-01-04 WO disclosed
WO-2000058500-A1 THE PREPARATION OF trans-4-AMINO-2-CYCLOPENTENE-1-CARBOXYLIC ACID DERIVATIVES CHIROTECH TECHNOLOGY LIMITED (GB) 2000-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052524-A1 Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters CPNE4, PYM1, CCNT1 MMP2 4155/4885ANPEP 700/4885CHRNB2 740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.