SCHEMBL993866

SCHEMBL993866

COC(=O)[C@@H]1C=C[C@H](N)C1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.37
ANPEP P15144 1/20 0.37
CHRNB2 P17787 2/20 0.34
CHRNA4 P43681 2/20 0.34
ABAT P80404 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2208895 1.00 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
SCHEMBL19337855 1.00 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
SCHEMBL993865 1.00 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
SCHEMBL14480001 1.00 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
Hydrochloric Acid SCHEMBL6079312 0.98 MMP2 (0.36) MMP2ANPEPCHRNB2CHRNA4ABAT
Hydrochloric Acid SCHEMBL4093850 0.98 MMP2 (0.36) MMP2ANPEPCHRNB2CHRNA4ABAT
Hydrochloric Acid SCHEMBL6081955 0.98 MMP2 (0.36) MMP2ANPEPCHRNB2CHRNA4ABAT
Hydrochloric Acid SCHEMBL4426352 0.98 MMP2 (0.36) MMP2ANPEPCHRNB2CHRNA4ABAT
Sulfuric Acid SCHEMBL6078882 0.93 MMP2 (0.33) MMP2ANPEPCHRNB2CHRNA4ABAT
Sulfuric Acid SCHEMBL6078890 0.93 MMP2 (0.33) MMP2ANPEPCHRNB2CHRNA4ABAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10385006-B2 Process for the preparation of amino alcohol derivatives or salts thereof GRANULES INDIA LIMITED (IN) 2019-08-20 US claimed
US-20170233329-A1 PROCESS FOR THE PREPARATION OF AMINO ALCOHOL DERIVATIVES OR SALTS THEREOF GRANULES INDIA LTD (IN) 2017-08-17 US claimed
US-6562861-B1 (1R,3R,4R,1'S)-(-)-(1'-acetylamino-2 '-ethyl)butyl-4-(aminoimino)methylaminocyclopentan-1-carboxylic acid was prepd. and tested in vitro as neuraminidase inhibitor (IC50 less-than 1.mu.M). Bactericides or viricides BIOCRYST PHARMACEUTICALS, INC. 2003-05-13 US claimed
CN-116507610-B Herbicidal malonamides 巴斯夫欧洲公司 2026-05-19 CN disclosed
US-12617803-B2 Condensed isoxazoline derivatives and their use as herbicides BASF SE (DE) 2026-05-05 US disclosed
US-12612394-B2 Herbicidal malonamides BASF SE (DE) 2026-04-28 US disclosed
EP-4683908-A1 SUBSTITUTED OXAZOLIDINONES AND IMIDAZOLINONES AS HERBICIDES FMC Corporation (US) 2026-01-28 EP disclosed
US-12389910-B2 Beta-lactams and their use as herbicides BASF SE (DE) 2025-08-19 US disclosed
CN-115515962-B Fused isoxazoline derivatives and their use as herbicides 巴斯夫欧洲公司 2025-04-29 CN disclosed
EP-4251609-B1 HERBICIDAL MALONAMIDES BASF SE (DE) 2025-04-23 EP disclosed
CN-119350339-A Preparation method and application of abacavir impurity 安徽贝克制药股份有限公司 2025-01-24 CN disclosed
WO-2011003061-A2 PRODUCTION OF TRAN S-4-AMINOCYCLOPENT-2-ENE-1-CARBOXYLIC ACID DERIVATIVES DR. REDDY'S LABORATORIES LTD. (IN) 2011-01-06 WO disclosed
WO-2009042013-A1 PROCESS FOR THE SYNTHESIS OF E1 ACTIVATING ENZYME INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. (US) 2009-04-02 WO disclosed
US-20090036678-A1 Process for the synthesis of E1 activating enzyme inhibitors MILLENNIUM PHARMACEUTICALS, INC. (US) 2009-02-05 US disclosed
US-20090036678-A1 Process for the synthesis of E1 activating enzyme inhibitors MILLENNIUM PHARMACEUTICALS, INC. (US) 2009-02-05 US disclosed
US-7038059-B2 Process for preparation of 4-n-substituted amino-2-aza-1-oxabicyclo[3.3.0] oct-2-ene-6-carboxylic acid esters and process for preparation of their intermediates KURARAY CO., LTD. (JP) 2006-05-02 US disclosed
US-20040121482-A1 Process for preparation of 4-n-substituted amino-2-aza-1-oxabicyclo[3.3.0] oct-2-ene-6-carboxylic acid esters and process for preparation of their intermediates KURARAY CO., LTD. (JP) 2004-06-24 US disclosed
EP-1334969-A1 PROCESS FOR PREPARATION OF 4-N-SUBSTITUTED AMINO-2-AZA-1-OXABICYCLO 3.3.0]OCT-2-ENE-6-CARBOXYLIC ACID ESTERS AND PROCESS FOR PREPARATION OF THEIR INTERMEDIATES KURARAY CO., LTD. (JP) 2003-08-13 EP disclosed
US-6495711-B2 1-(TERT-BUTOXYCARBONYLAMINO)-4-METHOXYCARBONYL-CYCLOPENT-2-ENE STARTING BY REACTING 2-AZABICYCLO(2.2.1)HEPT-5-EN-3-ONE WITH AN ALCOHOL AND NONAQUEOUS ACID; CHEMICAL INTERMEDIATES TO ANTIVIRAL AGENTS AGAINST INFLUENZA VIRUS BIOCRYST PHARMACEUTICALS INC. 2002-12-17 US disclosed
US-20020052524-A1 Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters BIOCRYST PHARMACEUTICALS, INC. 2002-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052524-A1 Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters CPNE4, PYM1, CCNT1 MMP2 4155/4885ANPEP 700/4885CHRNB2 740/4885
US-12617803-B2 Condensed isoxazoline derivatives and their use as herbicides CBR3, CBR1, GLRA3 MMP2 1856/4885ANPEP 4311/4885CHRNB2 1983/4885
US-20170233329-A1 PROCESS FOR THE PREPARATION OF AMINO ALCOHOL DERIVATIVES OR SALTS THEREOF ADH1C, ADH1A, ALDH7A1 MMP2 2709/4885ANPEP 316/4885CHRNB2 4332/4885
US-12612394-B2 Herbicidal malonamides CBR3, DDT, HACL2 MMP2 2456/4885ANPEP 1039/4885CHRNB2 1994/4885
US-10385006-B2 Process for the preparation of amino alcohol derivatives or salts thereof ADH1C, ADH1A, ALDH7A1 MMP2 2118/4885ANPEP 222/4885CHRNB2 4348/4885
US-12389910-B2 Beta-lactams and their use as herbicides POLL, HDHD5, GLRB MMP2 839/4885ANPEP 810/4885CHRNB2 2671/4885
US-20090036678-A1 Process for the synthesis of E1 activating enzyme inhibitors SULT1E1, SULT1A1, ALDH18A1 MMP2 1616/4885ANPEP 248/4885CHRNB2 3771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.