Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4093850

COC(=O)[C@@H]1C=C[C@H](N)C1.Cl

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRNB4 known ✓ P30926 1/20 0.33
CHRNA3 known ✓ P32297 1/20 0.33
CHRNA7 known ✓ P36544 1/20 0.33
MMP2 P08253 1/20 0.36
ANPEP P15144 1/20 0.36
CHRNB2 P17787 2/20 0.33
CHRNA4 P43681 2/20 0.33
ABAT P80404 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6081955 1.00 MMP2 (0.36) MMP2ANPEPCHRNB2CHRNA4ABAT
Hydrochloric Acid SCHEMBL6079312 1.00 MMP2 (0.36) MMP2ANPEPCHRNB2CHRNA4ABAT
Hydrochloric Acid SCHEMBL4426352 1.00 MMP2 (0.36) MMP2ANPEPCHRNB2CHRNA4ABAT
SCHEMBL14480001 0.98 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
SCHEMBL2208895 0.98 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
SCHEMBL19337855 0.98 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
SCHEMBL993865 0.98 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
SCHEMBL993866 0.98 MMP2 (0.37) MMP2ANPEPCHRNB2CHRNA4ABAT
Sulfuric Acid SCHEMBL6078885 0.91 MMP2 (0.33) MMP2ANPEPCHRNB2CHRNA4ABAT
Sulfuric Acid SCHEMBL6078882 0.91 MMP2 (0.33) MMP2ANPEPCHRNB2CHRNA4ABAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079801-A Synthesis method and analysis method of (1S, 4R) -4-amino-2-cyclopentene-1-carboxylic acid methyl ester tartrate 2026-05-26 CN claimed
EP-2546242-A1 Cannabinoid receptor ligands Abbott Laboratories (US) 2013-01-16 EP claimed
CN-122079801-A Synthesis method and analysis method of (1S, 4R) -4-amino-2-cyclopentene-1-carboxylic acid methyl ester tartrate 2026-05-26 CN disclosed
CN-122079801-A Synthesis method and analysis method of (1S, 4R) -4-amino-2-cyclopentene-1-carboxylic acid methyl ester tartrate 2026-05-26 CN disclosed
CN-116507610-B Herbicidal malonamides 巴斯夫欧洲公司 2026-05-19 CN disclosed
EP-4683908-A1 SUBSTITUTED OXAZOLIDINONES AND IMIDAZOLINONES AS HERBICIDES FMC Corporation (US) 2026-01-28 EP disclosed
US-12319664-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of cyclopentenylcarboxylic acid derivatives BAYER AKTIENGESELLSCHAFT (DE) 2025-06-03 US disclosed
EP-4251609-B1 HERBICIDAL MALONAMIDES BASF SE (DE) 2025-04-23 EP disclosed
WO-2025026808-A1 HERBICIDAL ALANINE ANALOGUES BASF SE (DE) 2025-02-06 WO disclosed
EP-4251606-B1 HERBICIDAL MALONAMIDES BASF SE (DE) 2025-01-22 EP disclosed
US-12185723-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of s-containing cyclopentenylcarboxylic esters BAYER AKTIENGESELLSCHAFT (DE) 2025-01-07 US disclosed
EP-1040094-B1 SUBSTITUTED CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS BIOCRYST PHARM INC (US) 2009-03-18 EP disclosed
US-20090036678-A1 Process for the synthesis of E1 activating enzyme inhibitors MILLENNIUM PHARMACEUTICALS, INC. (US) 2009-02-05 US disclosed
US-20060252774-A1 Regulation of type 5 adenylyl cyclase for treatment of neurodegenerative and cardiac diseases NEW JERSEY, UNIVERSITY OF MEDICINE AND DENTISTRY OF 2006-11-09 US disclosed
US-7038059-B2 Process for preparation of 4-n-substituted amino-2-aza-1-oxabicyclo[3.3.0] oct-2-ene-6-carboxylic acid esters and process for preparation of their intermediates KURARAY CO., LTD. (JP) 2006-05-02 US disclosed
US-20040121482-A1 Process for preparation of 4-n-substituted amino-2-aza-1-oxabicyclo[3.3.0] oct-2-ene-6-carboxylic acid esters and process for preparation of their intermediates KURARAY CO., LTD. (JP) 2004-06-24 US disclosed
EP-1334969-A1 PROCESS FOR PREPARATION OF 4-N-SUBSTITUTED AMINO-2-AZA-1-OXABICYCLO 3.3.0]OCT-2-ENE-6-CARBOXYLIC ACID ESTERS AND PROCESS FOR PREPARATION OF THEIR INTERMEDIATES KURARAY CO., LTD. (JP) 2003-08-13 EP disclosed
US-6562861-B1 (1R,3R,4R,1'S)-(-)-(1'-acetylamino-2 '-ethyl)butyl-4-(aminoimino)methylaminocyclopentan-1-carboxylic acid was prepd. and tested in vitro as neuraminidase inhibitor (IC50 less-than 1.mu.M). Bactericides or viricides BIOCRYST PHARMACEUTICALS, INC. 2003-05-13 US disclosed
US-6495711-B2 1-(TERT-BUTOXYCARBONYLAMINO)-4-METHOXYCARBONYL-CYCLOPENT-2-ENE STARTING BY REACTING 2-AZABICYCLO(2.2.1)HEPT-5-EN-3-ONE WITH AN ALCOHOL AND NONAQUEOUS ACID; CHEMICAL INTERMEDIATES TO ANTIVIRAL AGENTS AGAINST INFLUENZA VIRUS BIOCRYST PHARMACEUTICALS INC. 2002-12-17 US disclosed
US-20020052524-A1 Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters BIOCRYST PHARMACEUTICALS, INC. 2002-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052524-A1 Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters CPNE4, PYM1, CCNT1 CHRNB4 614/4885CHRNA3 1247/4885CHRNA7 846/4885
US-12319664-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of cyclopentenylcarboxylic acid derivatives AADAC, PRDX5, DDT CHRNB4 3822/4885CHRNA3 1742/4885CHRNA7 884/4885
US-12185723-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of s-containing cyclopentenylcarboxylic esters NOTUM, AADAC, DDT CHRNB4 4413/4885CHRNA3 2282/4885CHRNA7 2081/4885
US-20090036678-A1 Process for the synthesis of E1 activating enzyme inhibitors SULT1E1, SULT1A1, ALDH18A1 CHRNB4 3570/4885CHRNA3 4159/4885CHRNA7 3707/4885
US-20060252774-A1 Regulation of type 5 adenylyl cyclase for treatment of neurodegenerative and cardiac diseases ADCY5, ADCY6, ADCY2 CHRNB4 82/4885CHRNA3 77/4885CHRNA7 95/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.