Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 2/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FADS1 | O60427 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16621986 | 0.89 | SLC22A12 (0.39) | RXFP1ACLYPTPN2PTPN1PTPN5 | |
| SCHEMBL9939774 | 0.84 | RXFP1 (0.40) | RXFP1CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL9938594 | 0.83 | NAMPT (0.41) | RXFP1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL9939541 | 0.82 | CYP2D6 (0.38) | RXFP1CYP2D6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9939469 | 0.82 | CNR1 (0.44) | RXFP1CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL9939397 | 0.81 | IDH1 (0.40) | RXFP1MEN1KMT2ALMNAACLY | |
| SCHEMBL9939437 | 0.80 | RXFP1 (0.39) | RXFP1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL9939492 | 0.79 | CYP2D6 (0.40) | RXFP1CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL17279296 | 0.77 | FBP1 (0.38) | ACLYPTPN2PTPN1PTPN5SLC40A1 | |
| SCHEMBL9939525 | 0.74 | CYP2D6 (0.38) | RXFP1CYP2D6MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078869-A1 | PYRIDONYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |