Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 4/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939767 | 0.89 | HSD11B1 (0.43) | RXFP1HSD11B1L3MBTL1MEN1KMT2A | |
| SCHEMBL16621985 | 0.89 | FBP1 (0.38) | RXFP1HSD11B1L3MBTL1SLC40A1LMNA | |
| SCHEMBL9939768 | 0.86 | RXFP1 (0.43) | RXFP1HSD11B1L3MBTL1LMNA | |
| SCHEMBL16621987 | 0.83 | NAMPT (0.42) | RXFP1HSD11B1L3MBTL1MEN1KMT2A | |
| SCHEMBL9939397 | 0.83 | IDH1 (0.40) | RXFP1MEN1KMT2ALMNAIDH1 | |
| SCHEMBL16621982 | 0.83 | RXFP1 (0.40) | RXFP1HSD11B1L3MBTL1IDH1MAPT | |
| SCHEMBL9939557 | 0.83 | RXFP1 (0.47) | RXFP1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9939755 | 0.82 | SCN9A (0.41) | RXFP1HSD11B1L3MBTL1KDM4ELMNA | |
| SCHEMBL16621984 | 0.82 | RXFP1 (0.46) | RXFP1RELAMEN1KMT2ALMNA | |
| SCHEMBL9939753 | 0.80 | RXFP1 (0.37) | RXFP1HSD11B1L3MBTL1NFKBIARELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078869-A1 | PYRIDONYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |