Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 6/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939775 | 0.89 | DRD2 (0.40) | ENPP2CNR1TRPV1PTGESWDR5 | |
| SCHEMBL14238211 | 0.88 | CNR1 (0.36) | ENPP2CNR1TRPV1PTGESWDR5 | |
| SCHEMBL9939974 | 0.85 | PTGES (0.43) | ENPP2CNR1PTGES | |
| SCHEMBL9941944 | 0.84 | SMO (0.44) | ENPP2CNR1PTGESMEN1LMNA | |
| SCHEMBL9939834 | 0.83 | PTGES (0.38) | ENPP2CNR1TRPV1PTGESWDR5 | |
| SCHEMBL9939776 | 0.83 | PTGES (0.38) | ENPP2CNR1TRPV1PTGESWDR5 | |
| SCHEMBL9939831 | 0.82 | PTGES (0.41) | ENPP2CNR1PTGES | |
| SCHEMBL9899450 | 0.82 | MAP2K7 (0.41) | CNR1KCNH2HTTSMN1; SMN2 | |
| SCHEMBL9939772 | 0.82 | PPARD (0.39) | ENPP2CNR1PTGESWDR5 | |
| SCHEMBL9939824 | 0.82 | POLB (0.45) | ROCK2WDR5MEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076672-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |