Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939771 | 0.90 | PTGES (0.47) | SMOENPP2TP53LMNAMAPT | |
| SCHEMBL9939977 | 0.89 | PTGES (0.38) | ENPP2TP53LMNAMAPTCNR1 | |
| SCHEMBL9940039 | 0.89 | PTGES (0.38) | ENPP2TP53LMNAMAPTCNR1 | |
| SCHEMBL15033840 | 0.86 | PTGES (0.38) | ENPP2TP53LMNAMAPTCNR1 | |
| SCHEMBL14238584 | 0.86 | HPGD (0.41) | ENPP2TP53LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9939974 | 0.84 | PTGES (0.43) | SMOENPP2CNR1PTGES | |
| SCHEMBL9940038 | 0.84 | ALDH1A1 (0.40) | ENPP2TP53LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9939773 | 0.84 | AKT2 (0.42) | ENPP2MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9939775 | 0.83 | DRD2 (0.40) | ENPP2CNR1PTGES | |
| SCHEMBL9939834 | 0.82 | PTGES (0.38) | ENPP2MAPTSMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076672-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |