Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.62 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.60 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.60 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | GCGR | P47871 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966911 | 1.00 | LTA4H (0.62) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL9940347 | 0.99 | LTA4H (0.61) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL9966913 | 0.90 | LTA4H (0.62) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL9935250 | 0.89 | LTA4H (0.63) | LTA4HPSMB1PSMB5ESR1ESR2 | |
| SCHEMBL7106690 | 0.88 | ESR1 (0.61) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL9966912 | 0.87 | KDM4E (0.53) | LTA4HKDM4EALDH1A1HRH3 | |
| SCHEMBL9966810 | 0.87 | ESR1 (0.76) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL9966808 | 0.87 | ESR1 (0.76) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL9966792 | 0.85 | ESR1 (0.74) | PSMB1PSMB5PSMB2ESR1ESR2 | |
| SCHEMBL6594554 | 0.85 | ESR1 (0.71) | LTA4HPSMB1PSMB5PSMB2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |