Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 8/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966913 | 0.88 | LTA4H (0.62) | LTA4HHRH3 | |
| SCHEMBL9940347 | 0.88 | LTA4H (0.61) | KDM4ELTA4HHRH3ALDH1A1 | |
| SCHEMBL9966806 | 0.88 | ESR1 (0.60) | KDM4EHRH3SIGMAR1 | |
| SCHEMBL9966911 | 0.87 | LTA4H (0.62) | KDM4ELTA4HHRH3ALDH1A1 | |
| SCHEMBL9940230 | 0.87 | LTA4H (0.62) | KDM4ELTA4HHRH3ALDH1A1 | |
| SCHEMBL9967004 | 0.86 | LTA4H (0.50) | KDM4ELTA4HHRH3SIGMAR1ALDH1A1 | |
| SCHEMBL9940186 | 0.85 | HRH3 (0.51) | KDM4ELTA4HHRH3SIGMAR1ALDH1A1 | |
| SCHEMBL9935250 | 0.85 | LTA4H (0.63) | KDM4ELTA4H | |
| SCHEMBL9966786 | 0.84 | HRH3 (0.53) | KDM4ELTA4HHRH3SIGMAR1ALDH1A1 | |
| SCHEMBL9966830 | 0.84 | LTA4H (0.51) | KDM4ELTA4HHRH3SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |