Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940347 | 0.91 | LTA4H (0.61) | LTA4HHRH3ESR1ESR2GCGR | |
| SCHEMBL9966911 | 0.90 | LTA4H (0.62) | LTA4HHRH3ESR1ESR2GCGR | |
| SCHEMBL9940230 | 0.90 | LTA4H (0.62) | LTA4HHRH3ESR1ESR2GCGR | |
| SCHEMBL9966912 | 0.88 | KDM4E (0.53) | LTA4HHRH3 | |
| SCHEMBL9935250 | 0.88 | LTA4H (0.63) | LTA4HKMT2AESR1ESR2GCGR | |
| SCHEMBL9966807 | 0.87 | ESR1 (0.63) | LTA4HESR1ESR2 | |
| SCHEMBL9967005 | 0.85 | LTA4H (0.58) | LTA4HDRD3HRH3MEN1KMT2A | |
| SCHEMBL9966973 | 0.84 | LTA4H (0.57) | LTA4HDRD3HRH3MEN1KMT2A | |
| Ethylbenzene SCHEMBL7106162 | 0.84 | LTA4H (0.61) | LTA4HKMT2APSMB1PSMB5 | |
| SCHEMBL9966793 | 0.83 | LTA4H (0.56) | LTA4HDRD3HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |