Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfurous Acid SCHEMBL9940687 | 1.00 | SLC18A3 (0.42) | SLC18A3MAPTMEN1USP2LMNA | |
| SCHEMBL8972206 | 0.91 | HTR3A (0.44) | SLC18A3MAPTMEN1USP2LMNA | |
| SCHEMBL5271028 | 0.91 | HTR3A (0.44) | SLC18A3MAPTMEN1USP2LMNA | |
| Hydrochloric Acid SCHEMBL28701325 | 0.90 | HTR3A (0.43) | SLC18A3MAPTMEN1USP2LMNA | |
| SCHEMBL9182846 | 0.86 | SLC2A1 (0.41) | SLC18A3MAPTMEN1USP2LMNA | |
| SCHEMBL8517580 | 0.82 | IDO1 (0.45) | SLC18A3MAPTMEN1USP2LMNA | |
| SCHEMBL9311909 | 0.82 | IDO1 (0.45) | SLC18A3MAPTMEN1USP2LMNA | |
| SCHEMBL6853901 | 0.82 | HDAC2 (0.43) | CYP2C9POLBHDAC2ESR2 | |
| SCHEMBL10693588 | 0.81 | HTR3A (0.42) | SLC18A3MAPTMEN1USP2LMNA | |
| SCHEMBL9255070 | 0.77 | ESR2 (0.59) | CYP2C9HDAC2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598387-B2 | Process for the preparation of atovaquone | GLAXO GROUP LIMITED (GB) | 2013-12-03 | — | — | US | disclosed |
| EP-2651868-A2 | PROCESS FOR THE PREPARATION OF ATOVAQUONE | Glaxo Group Limited (GB) | 2013-10-23 | — | — | EP | disclosed |
| US-20130267717-A1 | PROCESS FOR THE PREPARATION OF ATOVAQUONE | GLAXO GROUP LIMITED (GB) | 2013-10-10 | — | — | US | disclosed |
| WO-2012080243-A2 | NOVEL PROCESS | GLAXO GROUP LIMITED (GB) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267717-A1 | PROCESS FOR THE PREPARATION OF ATOVAQUONE | DHPS, VKORC1, DPYD | SLC18A3 1878/4885MAPT 4190/4885MEN1 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.