Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940902 | 1.00 | KMT2A (0.37) | KMT2ACYP2C9CYP2C19ANPEPGRIN2D | |
| SCHEMBL9971048 | 1.00 | KMT2A (0.37) | KMT2ACYP2C9CYP2C19ANPEPGRIN2D | |
| SCHEMBL30804405 | 1.00 | KMT2A (0.37) | KMT2ACYP2C9CYP2C19ANPEPGRIN2D | |
| SCHEMBL9343752 | 0.84 | SIGMAR1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL22127330 | 0.82 | IDO1 (0.41) | — | |
| SCHEMBL11043767 | 0.78 | CHRM2 (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11046975 | 0.78 | CHRM2 (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL16985023 | 0.78 | ACHE (0.38) | KMT2A | |
| SCHEMBL11553791 | 0.74 | ANPEP (0.36) | KMT2ACYP2C9CYP2C19ANPEPSMN1; SMN2 | |
| SCHEMBL11545276 | 0.74 | ANPEP (0.36) | KMT2ACYP2C9CYP2C19ANPEPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651890-B1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| EP-2651890-A1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | Syngenta Participations AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080115-A1 | STRIGOLACTAM DERIVATIVES AND THEIR USE AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-06-21 | — | — | WO | disclosed |