Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | AOC2 | O75106 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27404979 | 0.73 | CYP19A1 (0.44) | QPCTMAPT | |
| SCHEMBL9940787 | 0.72 | NUDT1 (0.48) | QPCTAOC2 | |
| SCHEMBL11430315 | 0.70 | MAPT (0.39) | ALDH1A1MAPTLMNA | |
| SCHEMBL11076935 | 0.68 | LMNA (0.53) | ALDH1A1TP53MAPTLMNA | |
| SCHEMBL9777196 | 0.67 | TBXAS1 (0.85) | — | |
| SCHEMBL20570009 | 0.66 | CYP19A1 (0.71) | ALDH1A1TP53 | |
| SCHEMBL15654143 | 0.66 | GRM2 (0.37) | — | |
| SCHEMBL15894133 | 0.66 | KDM4E (0.76) | ALDH1A1TP53LMNA | |
| SCHEMBL10659297 | 0.66 | CYP1A2 (0.50) | — | |
| SCHEMBL11272924 | 0.66 | MAPT (0.62) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651903-A1 | BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | Janssen R&D Ireland (IE) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080446-A1 | BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | JANSSEN R&D IRELAND (IE) | 2012-06-21 | — | — | WO | disclosed |