SCHEMBL9941586

SCHEMBL9941586

Cc1cc(C(=O)NC2CCCCC2)nc(C)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.54
NPC1 O15118 7/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
TSHR P16473 2/20 0.54
HTT P42858 1/20 0.52
TAS1R3 Q7RTX0 2/20 0.51
TAS1R1 Q7RTX1 2/20 0.51
TAS1R2 Q8TE23 2/20 0.51
ALDH1A1 P00352 3/20 0.51
KDM4E B2RXH2 1/20 0.51
POLB P06746 1/20 0.51
CYP1A2 P05177 3/20 0.50
CYP2C19 P33261 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
S1PR1 P21453 1/20 0.50
ATM Q13315 1/20 0.50
SPR P35270 1/20 0.49
CNR1 P21554 1/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25474644 0.77 CD38 (0.50) RAB9ANPC1SMN1; SMN2TSHRHTT
SCHEMBL25474638 0.77 ALDH1A1 (0.47) RAB9ANPC1SMN1; SMN2TSHRHTT
SCHEMBL25474724 0.77 CD38 (0.49) RAB9ANPC1SMN1; SMN2TSHRHTT
SCHEMBL25489378 0.76 CD38 (0.69) RAB9ANPC1SMN1; SMN2TSHRALDH1A1
SCHEMBL22449358 0.76 ALDH1A1 (0.64) RAB9ANPC1SMN1; SMN2HTTALDH1A1
SCHEMBL22449346 0.75 LMNA (0.63) RAB9ANPC1SMN1; SMN2TSHRTAS1R3
SCHEMBL22883817 0.74 NPC1 (0.71) RAB9ANPC1SMN1; SMN2TSHRALDH1A1
SCHEMBL18698882 0.74 ALDH1A1 (0.56) RAB9ANPC1SMN1; SMN2TSHRTAS1R3
SCHEMBL19445811 0.72 HSD11B1 (0.71) RAB9ANPC1HTTALDH1A1KDM4E
SCHEMBL19445899 0.72 NPC1 (0.56) RAB9ANPC1SMN1; SMN2TSHRTAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012079583-A1 SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS AARHUS UNIVERSITET (DK) 2012-06-21 WO disclosed
WO-2012079583-A1 SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS AARHUS UNIVERSITET (DK) 2012-06-21 WO disclosed