SCHEMBL994193

SCHEMBL994193

FC1(F)CN(C2CCNCC2)C1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29165102 0.98 HPGD (0.31) ARG1ARG2
SCHEMBL2372681 0.83 DPP4 (0.37)
Hydrochloric Acid SCHEMBL23884910 0.81 DPP4 (0.36)
Hydrochloric Acid SCHEMBL3606485 0.81 DPP4 (0.36)
SCHEMBL3092435 0.81 TSHR (0.31)
SCHEMBL29090720 0.80 IRAK4 (0.37)
Hydrochloric Acid SCHEMBL484398 0.80 L3MBTL3 (0.30)
Hydrochloric Acid SCHEMBL26131034 0.78 IRAK4 (0.37)
SCHEMBL521969 0.77 HRH3 (0.39)
Hydrochloric Acid SCHEMBL30879255 0.76 ARG1 (0.33) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025077825-A1 METHODS AND COMPOSITIONS FOR TREATING CARDIO-PULMONARY DISORDERS FAUNA BIO INCORPORATED (US) 2025-04-17 WO disclosed
US-20240217978-A1 COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2024-07-04 US disclosed
US-12024499-B2 Muscarinic agonists HEPTARES THERAPEUTICS LIMITED (GB) 2024-07-02 US disclosed
US-12024499-B2 Muscarinic agonists HEPTARES THERAPEUTICS LIMITED (GB) 2024-07-02 US disclosed
US-12024499-B2 Muscarinic agonists HEPTARES THERAPEUTICS LIMITED (GB) 2024-07-02 US disclosed
US-20230002354-A1 MUSCARINIC AGONISTS NXERA PHARMA UK LIMITED (GB) 2023-01-05 US disclosed
US-20230002354-A1 MUSCARINIC AGONISTS NXERA PHARMA UK LIMITED (GB) 2023-01-05 US disclosed
WO-2022109492-A1 PYRROLOPYRIDAZINE COMPOUNDS AS KINASE INHIBITORS GOSSAMER BIOSERVICES, INC. (US) 2022-05-27 WO disclosed
US-11254656-B2 Muscarinic agonists HEPTARES THERAPEUTICS LIMITED (GB) 2022-02-22 US disclosed
US-11254656-B2 Muscarinic agonists HEPTARES THERAPEUTICS LIMITED (GB) 2022-02-22 US disclosed
WO-2010138589-A1 BICYCLIC PYRIMIDINE PI3K INHIBITOR COMPOUNDS SELECTIVE FOR P110 DELTA, AND METHODS OF USE GENENTECH, INC. (US) 2010-12-02 WO disclosed
WO-2010138589-A1 BICYCLIC PYRIMIDINE PI3K INHIBITOR COMPOUNDS SELECTIVE FOR P110 DELTA, AND METHODS OF USE GENENTECH, INC. (US) 2010-12-02 WO disclosed
CN-101868464-A Thienopyrimidiene derivatives as PI3k inhibitors HOFFMANN LA ROCHE 2010-10-20 CN disclosed
EP-2215090-A1 PURINE DERIVATIVES USEFUL AS PI3 KINASE INHIBITORS F. Hoffmann-La Roche AG (CH) 2010-08-11 EP disclosed
EP-2205610-A1 THIENOPYRIMIDIENE DERIVATIVES AS PI3K INHIBITORS F. Hoffmann-Roche AG (CH) 2010-07-14 EP disclosed
WO-2009053715-A1 THIENOPYRIMIDIENE DERIVATIVES AS PI3K INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2009-04-30 WO disclosed
WO-2009053715-A1 THIENOPYRIMIDIENE DERIVATIVES AS PI3K INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2009-04-30 WO disclosed
WO-2009053716-A1 PURINE DERIVATIVES USEFUL AS PI3 KINASE INHIBITORS F.HOFFMANN-LA ROCHE AG (CH) 2009-04-30 WO disclosed
WO-2009053716-A1 PURINE DERIVATIVES USEFUL AS PI3 KINASE INHIBITORS F.HOFFMANN-LA ROCHE AG (CH) 2009-04-30 WO disclosed
WO-2008152394-A1 PHARMACEUTICAL COMPOUNDS F.HOFFMANN-LA ROCHE AG (CH) 2008-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002354-A1 MUSCARINIC AGONISTS CHRM1, CHRM2, CHRM3 ARG1 346/4885ARG2 797/4885
US-11254656-B2 Muscarinic agonists CHRM1, CHRM2, CHRM3 ARG1 346/4885ARG2 797/4885
US-12024499-B2 Muscarinic agonists CHRM1, CHRM2, CHRM3 ARG1 346/4885ARG2 797/4885
US-20240217978-A1 COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME ADORA2A, ADORA1, ADORA2B ARG1 3806/4885ARG2 3541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.