Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.66 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.66 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19585205 | 0.92 | ALDH1A1 (0.61) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL28211157 | 0.87 | ALDH1A1 (0.70) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL10443431 | 0.87 | CYP3A4 (0.66) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL12955064 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL22927059 | 0.84 | TSHR (0.47) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL12499482 | 0.83 | MAPT (0.56) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL12329596 | 0.81 | ALDH1A1 (0.72) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL11343876 | 0.81 | ALDH1A1 (0.79) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL1529083 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4TSHRHPGD | |
| SCHEMBL18299297 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250205344-A1 | 2,4-DIOXOTETRAHYDROPYRIMIDINYL DERATIVES AS DEGRONS IN PROTACS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2025-06-26 | — | — | US | disclosed |
| EP-4499628-A1 | 2,4-DIOXOTETRAHYDROPYRIMIDINYL DERIVATIVES AS DEGRONS IN PROTACS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2025-02-05 | — | — | EP | disclosed |
| CN-117924087-A | Safe and environment-friendly preparation method of dinitroaromatic hydrocarbon | 福州大学 | 2024-04-26 | — | — | CN | disclosed |
| US-11806661-B2 | Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound | FUJIFILM CORPORATION (JP) | 2023-11-07 | — | — | US | disclosed |
| US-11806661-B2 | Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound | FUJIFILM CORPORATION (JP) | 2023-11-07 | — | — | US | disclosed |
| WO-2023180388-A1 | 2,4-DIOXOTETRAHYDROPYRIMIDINYL DERIVATIVES AS DEGRONS IN PROTACS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-09-28 | — | — | WO | disclosed |
| US-20230225201-A1 | Organic Light Emitting Diode and Device Comprising the Same | NOVALED GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
| US-20210394113-A1 | POLYMER AND METHOD FOR PRODUCING THE SAME, GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, AND GAS SEPARATION APPARATUS USING THE POLYMER, AND m-PHENYLENEDIAMINE COMPOUND | FUJIFILM CORPORATION (JP) | 2021-12-23 | — | — | US | disclosed |
| CN-107840826-B | 1H-indazole derivatives and application thereof as IDO (intermediate bonded oxygen) inhibitor | 西华大学 | 2021-07-09 | — | — | CN | disclosed |
| US-9175006-B2 | Compositions and methods for cyclofructans as separation agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-11-03 | — | — | US | disclosed |
| US-20100130496-A1 | PYRIMIDINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2010-05-27 | — | — | US | disclosed |
| EP-2150546-A2 | PYRIMIDINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE | F. Hoffmann-Roche AG (CH) | 2010-02-10 | — | — | EP | disclosed |
| EP-2146981-A1 | PHARMACEUTICAL COMPOUNDS | F. Hoffmann-Roche AG (CH) | 2010-01-27 | — | — | EP | disclosed |
| US-20100016306-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-01-21 | — | — | US | disclosed |
| WO-2009053715-A1 | THIENOPYRIMIDIENE DERIVATIVES AS PI3K INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-04-30 | — | — | WO | disclosed |
| EP-2032582-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008125833-A1 | PHARMACEUTICAL COMPOUNDS | PIRAMED LIMITED (GB) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008125839-A2 | PYRIMIDINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE | PIRAMED LIMITED (GB) | 2008-10-23 | — | — | WO | disclosed |
| WO-2007122410-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007122410-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210394113-A1 | POLYMER AND METHOD FOR PRODUCING THE SAME, GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, AND GAS SEPARATION APPARATUS USING THE POLYMER, AND m-PHENYLENEDIAMINE COMPOUND | PRMT9, PRMT1, PNMT | ALDH1A1 2452/4885TDP1 2677/4885CYP3A4 1289/4885 |
| US-20100130496-A1 | PYRIMIDINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE | PIK3CA, PIP5K1B, PIK3CD | ALDH1A1 2499/4885TDP1 380/4885CYP3A4 1720/4885 |
| US-20100016306-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITORS | PIK3CA, PIK3CD, PIK3CB | ALDH1A1 2864/4885TDP1 256/4885CYP3A4 1610/4885 |
| US-20250205344-A1 | 2,4-DIOXOTETRAHYDROPYRIMIDINYL DERATIVES AS DEGRONS IN PROTACS | CRBN, AR, GNRHR | ALDH1A1 3146/4885TDP1 3924/4885CYP3A4 1468/4885 |
| US-11806661-B2 | Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound | PRMT9, PRMT1, PNMT | ALDH1A1 2452/4885TDP1 2677/4885CYP3A4 1289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.