Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955006 | 0.69 | LMNA (0.42) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL8868709 | 0.67 | MAPT (0.42) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL24256856 | 0.64 | ITGB2 (0.64) | LMNAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL16765743 | 0.63 | HTT (0.50) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL9715453 | 0.62 | KDM1A (0.48) | LMNAMAPTALDH1A1CYP1A2HTR1A | |
| SCHEMBL15283315 | 0.61 | TMEM97 (0.63) | SMN1; SMN2CYP1A2HTR1ACYP2D6DRD2 | |
| SCHEMBL24169983 | 0.61 | NOTUM (0.43) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Bromide SCHEMBL9694632 | 0.61 | KDM1A (0.47) | LMNAMAPTALDH1A1CYP1A2HTR1A | |
| SCHEMBL2955005 | 0.60 | HSD17B3 (0.47) | LMNAMAPTMEN1KMT2AHTT | |
| SCHEMBL9480881 | 0.60 | GRIA1 (0.41) | LMNAMEN1KMT2AALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651219-A2 | FUNGICIDAL AZOCYCLIC AMIDES | E.I. Du Pont De Nemours And Company (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082580-A2 | FUNGICIDAL AZOCYCLIC AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |