Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 4/20 | 0.40 |
| ▸ | CCND1 | P24385 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR5A | P47898 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943341 | 0.93 | HTR1A (0.48) | SLC6A4CDK4CCND1HTR1BHTR1A | |
| Acetamide SCHEMBL9943944 | 0.90 | HTR1A (0.45) | CDK4CCND1HTR1BHTR1AHTR5A | |
| SCHEMBL9943336 | 0.84 | MC5R (0.48) | CDK4CCND1KDM4ECYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL9943307 | 0.84 | MC5R (0.48) | CDK4CCND1LMNA | |
| SCHEMBL9943326 | 0.83 | MC5R (0.46) | CDK4CCND1LMNA | |
| SCHEMBL9943288 | 0.83 | MC5R (0.46) | CDK4CCND1LMNA | |
| SCHEMBL9943349 | 0.77 | MC5R (0.49) | CDK4CCND1KDM4ECYP3A4TSHR | |
| SCHEMBL9943313 | 0.76 | MC5R (0.48) | CDK4CCND1LMNAKMT2A | |
| SCHEMBL9943282 | 0.73 | MC5R (0.47) | CDK4CCND1ALDH1A1KMT2A | |
| SCHEMBL7250093 | 0.73 | SIGMAR1 (0.45) | SLC6A4MTNR1AMTNR1BTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | claimed |
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | disclosed |