Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 11/20 | 0.48 |
| ▸ | MC3R | P41968 | 11/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GOT1 | P17174 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943349 | 0.91 | MC5R (0.49) | MC5RMC3RCDK4CCND1MC4R | |
| SCHEMBL9943335 | 0.89 | GOT1 (0.49) | MC5RMC3RCDK4CCND1MC4R | |
| SCHEMBL9943288 | 0.88 | MC5R (0.46) | MC5RMC3RCDK4CCND1MC4R | |
| SCHEMBL9943326 | 0.88 | MC5R (0.46) | MC5RMC3RCDK4CCND1MC4R | |
| SCHEMBL9943336 | 0.85 | MC5R (0.48) | MC5RMC3RCDK4CCND1MC4R | |
| Hydrochloric Acid SCHEMBL9943307 | 0.85 | MC5R (0.48) | MC5RMC3RCDK4CCND1MC4R | |
| SCHEMBL9943325 | 0.84 | HPGD (0.44) | MC5RMC3RCDK4CCND1MC4R | |
| SCHEMBL9943264 | 0.80 | GOT1 (0.50) | MC5RMC3RCDK4CCND1MC4R | |
| SCHEMBL9943341 | 0.77 | HTR1A (0.48) | MC5RCDK4CCND1MC4RMEN1 | |
| SCHEMBL9943315 | 0.77 | GOT1 (0.44) | MC5RMC3RCDK4CCND1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | claimed |
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | disclosed |