Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 2/20 | 0.49 |
| ▸ | MC5R | P33032 | 6/20 | 0.49 |
| ▸ | MC3R | P41968 | 6/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 3/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943264 | 0.91 | GOT1 (0.50) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL9943313 | 0.89 | MC5R (0.48) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL9943315 | 0.87 | GOT1 (0.44) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL9943323 | 0.87 | GOT1 (0.44) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL2789272 | 0.86 | GOT1 (0.50) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL9943282 | 0.85 | MC5R (0.47) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL9943325 | 0.85 | HPGD (0.44) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL2788142 | 0.83 | GOT1 (0.53) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL9943439 | 0.82 | MC5R (0.47) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL9943267 | 0.82 | MC5R (0.49) | MC5RMC3RCDK4CCND1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | claimed |
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | disclosed |