Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 1/20 | 0.50 |
| ▸ | MC5R | P33032 | 10/20 | 0.49 |
| ▸ | MC3R | P41968 | 10/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788142 | 0.97 | GOT1 (0.53) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL9943264 | 0.91 | GOT1 (0.50) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL2788365 | 0.89 | GOT1 (0.49) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL9943439 | 0.88 | MC5R (0.47) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL2789631 | 0.88 | KMT2A (0.53) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2789684 | 0.86 | GOT1 (0.52) | GOT1CDK4CCND1MEN1KMT2A | |
| SCHEMBL9943335 | 0.86 | GOT1 (0.49) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL9943282 | 0.85 | MC5R (0.47) | GOT1MC5RMC3RCDK4CCND1 | |
| SCHEMBL9943267 | 0.85 | MC5R (0.49) | MC5RMC3RCDK4CCND1MEN1 | |
| SCHEMBL2787985 | 0.84 | MC5R (0.43) | GOT1MC5RMC3RCDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227502-B2 | Amides acting on the adenosine receptors | ANAMAR AB (SE) | 2012-07-24 | — | — | US | claimed |
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | claimed |
| US-20100098629-A1 | Novel Amides Acting on the Adenosine Receptors | ACURE PHARMA AB (SE) | 2010-04-22 | — | — | US | claimed |
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | disclosed |
| US-20100098629-A1 | Novel Amides Acting on the Adenosine Receptors | ACURE PHARMA AB (SE) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100098629-A1 | Novel Amides Acting on the Adenosine Receptors | ADORA1, ADORA3, ADORA2B | GOT1 1175/4885MC5R 328/4885MC3R 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.