Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943432 | 1.00 | ADRB2 (0.36) | ADRB2ADRB1ADRB3MAPTLMNA | |
| SCHEMBL11920542 | 0.85 | KMT2A (0.38) | ADRB2ADRB1ADRB3MAPTLMNA | |
| SCHEMBL11907845 | 0.85 | KMT2A (0.38) | ADRB2ADRB1ADRB3MAPTLMNA | |
| SCHEMBL11920540 | 0.85 | KMT2A (0.38) | ADRB2ADRB1ADRB3MAPTLMNA | |
| SCHEMBL9943465 | 0.82 | LMNA (0.37) | ADRB2ADRB1ADRB3LMNABTN3A1 | |
| SCHEMBL9943463 | 0.82 | LMNA (0.37) | ADRB2ADRB1ADRB3LMNABTN3A1 | |
| SCHEMBL9943640 | 0.82 | LMNA (0.37) | ADRB2ADRB1ADRB3LMNABTN3A1 | |
| SCHEMBL9943524 | 0.81 | LMNA (0.33) | ADRB2ADRB1ADRB3LMNABTN3A1 | |
| SCHEMBL9943652 | 0.81 | LMNA (0.33) | ADRB2ADRB1ADRB3LMNABTN3A1 | |
| SCHEMBL9943525 | 0.81 | LMNA (0.33) | ADRB2ADRB1ADRB3LMNABTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465847-B1 | AZETIDINONE COMPOUNDS AND MEDICAL USE THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2016-10-12 | — | — | EP | disclosed |
| US-8623855-B2 | Azetidinone compounds and medical use thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2014-01-07 | — | — | US | disclosed |
| US-20120208994-A1 | AZETIDINONE COMPOUNDS AND MEDICAL USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2012-08-16 | — | — | US | disclosed |
| EP-2465847-A1 | AZETIDINONE COMPOUNDS AND MEDICAL USE THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2012-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208994-A1 | AZETIDINONE COMPOUNDS AND MEDICAL USE THEREOF | CYP46A1, APOB, CETP | ADRB2 350/4885ADRB1 142/4885ADRB3 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.