SCHEMBL994386

SCHEMBL994386

N#Cc1cccc(-c2ccccn2)n1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.63
LMNA P02545 3/20 0.63
CCR1 P32246 3/20 0.63
CCR5 P51681 3/20 0.63
CCR8 P51685 3/20 0.63
TP53 P04637 3/20 0.63
ALOX15 P16050 2/20 0.63
HTT P42858 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
ALPL P05186 1/20 0.63
HSP90AA1 P07900 1/20 0.63
ALPI P09923 1/20 0.63
ALPG P10696 1/20 0.63
MAPK1 P28482 1/20 0.63
METAP1 P53582 2/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
BLM P54132 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL28311873 0.93 KDM4E (0.55) KDM4ELMNACCR1CCR5CCR8
SCHEMBL14297293 0.86 CTSS (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29988787 0.85 CTSS (0.55) KDM4ELMNACCR1CCR5CCR8
SCHEMBL9220648 0.85 CTSS (0.55) KDM4ELMNACCR1CCR5CCR8
SCHEMBL1771966 0.83 CTSS (0.53) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30615716 0.82 KDM4E (0.47) KDM4ELMNACCR1CCR5CCR8
Terpyridine SCHEMBL30610399 0.81 KDM4E (0.95) KDM4ELMNACCR1CCR5CCR8
Terpyridine SCHEMBL30610400 0.81 KDM4E (0.95) KDM4ELMNACCR1CCR5CCR8
SCHEMBL15819400 0.81 KDM4E (0.63) KDM4ELMNACCR1CCR5CCR8
SCHEMBL31754524 0.80 KDM4E (0.48) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250362307-A1 PHOTOACTIVE ANTIBODY CONJUGATE LIAO JUNG CHI (TW) 2025-11-27 US claimed
EP-4473309-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2024-12-11 EP claimed
CN-119013558-A Photoactivated antibody conjugates 新析生物科技股份有限公司 2024-11-22 CN claimed
WO-2023196986-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2023-10-12 WO claimed
CN-113713858-B Alpha alkylation reaction catalyst of nitrile and preparation method thereof 郑州大学 2023-06-23 CN claimed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-113713858-A Alpha alkylation reaction catalyst of nitrile and preparation method thereof 郑州大学 2021-11-30 CN claimed
CN-113559939-A Alpha alkylation reaction catalyst for nitrile and preparation method thereof 郑州大学 2021-10-29 CN claimed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
CN-110003284-A Containing asymmetric pincerlike ruthenium compound of pyridine-pyridine-benzenesulfonyl imidazoline and preparation method thereof 郑州大学 2019-07-12 CN claimed
EP-2868661-B1 BIPYRIDYL TRIAZOLE RARE EARTH COMPLEX AND PREPARATION PROCESS THEREFOR GUANGDONG SYNYOO NEW MATERIAL CO LTD (CN) 2016-11-09 EP claimed
EP-2868661-A1 BIPYRIDYL TRIAZOLE RARE EARTH COMPLEX AND PREPARATION PROCESS THEREFOR Guangdong Synyoo New Material Co. Ltd. (CN) 2015-05-06 EP claimed
US-8853399-B1 Bipyridine triazole type rare earth complex and preparation method thereof GUANGDONG SYNYOO NEW MATERIAL CO., LTD. (CN) 2014-10-07 US claimed
US-20140288305-A1 BIPYRIDINE TRIAZOLE TYPE RARE EARTH COMPLEX AND PREPARATION METHOD THEREOF GUANGDONG SYNYOO NEW MATERIAL CO., LTD. (CN) 2014-09-25 US claimed
US-20250362307-A1 PHOTOACTIVE ANTIBODY CONJUGATE LIAO JUNG CHI (TW) 2025-11-27 US disclosed
US-20250074925-A1 RARE EARTH COMPLEX SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2025-03-06 US disclosed
CN-119039358-B Lattice type iron-based complex based on cis-trans-isomerism triazole and preparation method thereof 西北工业大学 2025-02-18 CN disclosed
US-20050032786-A1 1, 3-benzothiazinone derivatives and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-02-10 US disclosed
EP-1424336-A1 1,3-BENZOTHIAZINONE DERIVATIVES AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-06-02 EP disclosed
EP-0850322-B1 SELECTIVE SEPARATION OF DISSOLVED METAL SPECIES WITH SUBSTITUTED 1,3,5 TRIAZINE EXTRACTANTS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2001-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140288305-A1 BIPYRIDINE TRIAZOLE TYPE RARE EARTH COMPLEX AND PREPARATION METHOD THEREOF LAS1L, RUVBL1, PDCD2L KDM4E 3902/4885LMNA 1357/4885CCR1 3156/4885
US-20050032786-A1 1, 3-benzothiazinone derivatives and use thereof MIF, MORF4L1, FOXM1 KDM4E 3627/4885LMNA 1854/4885CCR1 199/4885
US-20250074925-A1 RARE EARTH COMPLEX L1CAM, CHRM1, NPM1 KDM4E 4590/4885LMNA 674/4885CCR1 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.