Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299909 | 0.85 | ALDH1A1 (0.54) | ALDH1A1CYP1A2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL299908 | 0.84 | ALDH1A1 (0.53) | ALDH1A1CYP1A2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL12932112 | 0.83 | ALDH1A1 (0.48) | ALDH1A1CYP1A2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL21240 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL21239 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL12932150 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL291947 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CYP1A2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL291949 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL4067427 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TSHRTDP1SMN1; SMN2 | |
| SCHEMBL291948 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TSHRTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247927-A1 | NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF STICKY ENDED POLYNUCLEOTIDES | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2020-12-10 | — | — | WO | claimed |
| US-20110009607-A1 | METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END | THE UNIVERSITY OF TOKYO (JP) | 2011-01-13 | — | — | US | claimed |
| EP-2270142-A1 | METHOD OF PREPARING DNA FRAGMENT HAVING STICKY END | The University of Tokyo (JP) | 2011-01-05 | — | — | EP | claimed |
| US-20220251639-A1 | OLIGONUCLEOTIDE, OMICS ANALYSIS METHOD, AND OMICS ANALYSIS KIT | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2022-08-11 | — | — | US | disclosed |
| US-20220162687-A1 | NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF STICKY ENDED POLYNUCLEOTIDES | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2022-05-26 | — | — | US | disclosed |
| EP-3974528-A1 | OLIGONUCLEOTIDE, OMICS ANALYSIS METHOD, AND OMICS ANALYSIS KIT | Kyushu University, National University Corporation (JP) | 2022-03-30 | — | — | EP | disclosed |
| WO-2020247927-A1 | NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF STICKY ENDED POLYNUCLEOTIDES | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2020-12-10 | — | — | WO | disclosed |
| US-20110009607-A1 | METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END | THE UNIVERSITY OF TOKYO (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2270142-A1 | METHOD OF PREPARING DNA FRAGMENT HAVING STICKY END | The University of Tokyo (JP) | 2011-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009607-A1 | METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END | POLB, POLL, POLN | ALDH1A1 2795/4885CYP1A2 4089/4885TSHR 1820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.