Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944805 | 0.89 | ALDH1A1 (0.52) | KMT2AMEN1L3MBTL1MAPTMAPK1 | |
| SCHEMBL9945021 | 0.86 | KMT2A (0.49) | KMT2AMEN1L3MBTL1MAPTMAPK1 | |
| SCHEMBL9945018 | 0.85 | ALDH1A1 (0.42) | KMT2AMEN1L3MBTL1MAPTMAPK1 | |
| SCHEMBL9945015 | 0.84 | MAPT (0.42) | KMT2AMEN1MAPTMAPK1ALDH1A1 | |
| SCHEMBL9944804 | 0.80 | MAPT (0.48) | KMT2AMEN1L3MBTL1MAPTMAPK1 | |
| SCHEMBL9945035 | 0.80 | L3MBTL1 (0.54) | KMT2AMEN1L3MBTL1MAPTMAPK1 | |
| SCHEMBL9944774 | 0.80 | L3MBTL1 (0.48) | KMT2AMEN1L3MBTL1MAPTMAPK1 | |
| SCHEMBL9898485 | 0.77 | PTGES (0.47) | MAPTMAPK1ALDH1A1LMNANPC1 | |
| SCHEMBL9945019 | 0.77 | ALDH1A1 (0.44) | KMT2AMEN1L3MBTL1MAPTMAPK1 | |
| SCHEMBL9944972 | 0.77 | MAPT (0.56) | KMT2AMEN1L3MBTL1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | KMT2A 3376/4885MEN1 4598/4885L3MBTL1 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.