Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825639 | 0.88 | KDM1A (0.46) | KDM1AL3MBTL1TUBB1KCNQ3KCNQ2 | |
| SCHEMBL8351 | 0.88 | KDM1A (0.46) | KDM1AL3MBTL1TUBB1KCNQ3KCNQ2 | |
| SCHEMBL9945988 | 0.85 | THRA (0.43) | L3MBTL1CYP1A2CYP2C19TDP1SMN1; SMN2 | |
| SCHEMBL9945921 | 0.79 | RORC (0.49) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL14205345 | 0.77 | LMNA (0.46) | L3MBTL1TDP1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL257900 | 0.76 | CA1 (0.45) | KDM1AL3MBTL1TUBB1CYP1A2CYP2D6 | |
| SCHEMBL6349214 | 0.75 | KDM1A (0.44) | KDM1AL3MBTL1TUBB1KCNQ3KCNQ2 | |
| SCHEMBL177284 | 0.75 | MAPT (0.40) | L3MBTL1PDE4DUSP2HSD17B10ALDH1A1 | |
| SCHEMBL1510012 | 0.74 | KDM1A (0.50) | KDM1AL3MBTL1TUBB1KCNQ3KCNQ2 | |
| SCHEMBL2850890 | 0.74 | HTT (0.45) | KDM1AL3MBTL1HSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | KDM1A 4657/4885L3MBTL1 4393/4885TUBB1 2643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.