Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273282 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EESR1AHRSMN1; SMN2 | |
| SCHEMBL5883815 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EESR1AHRSMN1; SMN2 | |
| SCHEMBL16954460 | 0.83 | BRD4 (0.39) | ALDH1A1PTGS2KDM4EESR1AHR | |
| SCHEMBL16958934 | 0.83 | PTGS2 (0.38) | ALDH1A1PTGS2KDM4EESR1AHR | |
| SCHEMBL12180749 | 0.81 | PTGS2 (0.46) | ALDH1A1PTGS2KDM4EESR1AHR | |
| SCHEMBL16090021 | 0.81 | NQO1 (0.46) | ALDH1A1PTGS2KDM4EAKR1C3AKR1C2 | |
| SCHEMBL309509 | 0.80 | ALDH1A1 (0.45) | TYRALDH1A1PTGS2ESR1AHR | |
| SCHEMBL3579166 | 0.79 | ALDH1A1 (0.39) | ALDH1A1PTGS2KDM4EESR1AHR | |
| SCHEMBL5882247 | 0.79 | ALDH1A3 (0.50) | ALDH1A1PTGS2KDM4EESR1AHR | |
| SCHEMBL11683532 | 0.77 | ALDH1A1 (0.41) | ALDH1A1PTGS2KDM4EESR1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | TYR 2328/4885ALDH1A1 4010/4885PTGS2 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.