Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945978 | 0.84 | CYP1A2 (0.39) | GRM2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9893705 | 0.74 | SMN1; SMN2 (0.36) | GRM2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL12360656 | 0.73 | CSNK2A1 (0.40) | SMN1; SMN2GLAL3MBTL1MEN1NPC1 | |
| SCHEMBL9945974 | 0.73 | ESR1 (0.38) | GRM2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL11994372 | 0.71 | FAAH (0.43) | CYP1A2CYP2C9CYP2C19SMN1; SMN2GLA | |
| SCHEMBL15131365 | 0.71 | L3MBTL1 (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2GLA | |
| SCHEMBL9685182 | 0.71 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19SMN1; SMN2GLA | |
| SCHEMBL1311491 | 0.70 | SMN1; SMN2 (0.49) | CYP1A2CYP2C9CYP2C19SMN1; SMN2GLA | |
| SCHEMBL15120786 | 0.69 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19SMN1; SMN2GLA | |
| SCHEMBL16025495 | 0.69 | HPGD (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | GRM2 61/4885CYP1A2 2891/4885CYP2C9 4298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.