Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | PPM1A | P35813 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953495 | 0.90 | CYP1A2 (0.42) | CYP1A2CYP2C19L3MBTL1CYP2D6TDP1 | |
| SCHEMBL16034890 | 0.90 | CYP1A2 (0.42) | CYP1A2CYP2C19L3MBTL1CYP2D6TDP1 | |
| SCHEMBL9945990 | 0.88 | FAAH (0.41) | CYP1A2CYP2C19L3MBTL1CYP2D6TDP1 | |
| SCHEMBL9945923 | 0.85 | L3MBTL1 (0.44) | CYP1A2CYP2C19L3MBTL1CYP2D6TDP1 | |
| SCHEMBL29951322 | 0.82 | HTR2C (0.43) | CYP1A2CYP2C19L3MBTL1CYP2D6TDP1 | |
| SCHEMBL14988246 | 0.82 | HTR2C (0.43) | CYP1A2CYP2C19L3MBTL1CYP2D6TDP1 | |
| SCHEMBL3316395 | 0.81 | FAAH (0.43) | CYP1A2CYP2C19L3MBTL1CYP2D6TDP1 | |
| SCHEMBL25345554 | 0.78 | ENPP2 (0.39) | CYP1A2CYP2C19L3MBTL1CYP2D6TDP1 | |
| SCHEMBL9632842 | 0.78 | FAAH (0.43) | CYP1A2CYP2C19L3MBTL1CYP2D6TDP1 | |
| SCHEMBL29952280 | 0.76 | S1PR3 (0.42) | L3MBTL1FAAHMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | CYP1A2 2891/4885CYP2C19 3767/4885L3MBTL1 4393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.