Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9946050 | 0.87 | LIPE (0.73) | LIPESMN1; SMN2MAPTL3MBTL1MAPK1 | |
| SCHEMBL2559341 | 0.86 | LIPE (0.77) | LIPESMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL9946048 | 0.86 | LIPE (0.57) | LIPESMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL7606605 | 0.78 | RXRA (0.65) | LIPESMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL31556121 | 0.75 | APP (0.54) | LIPESMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL12908047 | 0.75 | MAPT (0.52) | SMN1; SMN2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL11083620 | 0.75 | MAPT (0.52) | LIPESMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL31556117 | 0.75 | HPGD (0.61) | SMN1; SMN2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL11091137 | 0.75 | APP (0.69) | SMN1; SMN2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL28931748 | 0.75 | MAPT (0.52) | LIPESMN1; SMN2ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | LIPE 3056/4885SMN1; SMN2 3273/4885ALDH1A1 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.