Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204758 | 0.80 | GAA (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL5256895 | 0.80 | MGAM (0.55) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL66328 | 0.79 | GAA (0.64) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL1792560 | 0.76 | GAA (0.41) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL13141063 | 0.75 | MGAM (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL28518326 | 0.73 | TSHR (0.33) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL807413 | 0.73 | PRKCA (0.42) | GAA | |
| SCHEMBL2759397 | 0.73 | MGAM (0.62) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL5256898 | 0.73 | MGAM (0.42) | MGAMGAASIMGAM2TSHR | |
| Acetone SCHEMBL6053753 | 0.73 | MGAM (0.48) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8899745-B2 | Ophthalmic lenses modified with functional groups and methods of making thereof | NOVARTIS AG (CH) | 2014-12-02 | — | — | US | disclosed |
| US-20120147323-A1 | OPHTHALMIC LENSES MODIFIED WITH FUNCTIONAL GROUPS AND METHODS OF MAKING THEREOF | ALCON INC. (CH) | 2012-06-14 | — | — | US | disclosed |