SCHEMBL66328

SCHEMBL66328

CCOC(=O)CC(=O)C(C)(C)C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.64
MGAM O43451 1/20 0.64
SI P14410 1/20 0.64
MGAM2 Q2M2H8 1/20 0.64
ALDH1A1 P00352 4/20 0.46
TRPA1 O75762 1/20 0.46
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP1A2 P05177 1/20 0.40
ALOX15 P16050 2/20 0.39
SOAT1 P35610 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27825811 0.98 GAA (0.61) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL6935043 0.89 GAA (0.56) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL17017228 0.88 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL1806665 0.88 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL1792560 0.82 GAA (0.41) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7232689 0.82 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL27805261 0.82 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL6248725 0.82 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL27493986 0.82 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL15286697 0.82 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058991-A Low ash content polypropylene resin and preparation method thereof 中国石油天然气股份有限公司 2025-05-30 CN claimed
US-20230167310-A1 CURING CATALYST AND RESIN COMPOSITION KOEI CHEMICAL COMPANY, LIMITED (JP) 2023-06-01 US claimed
EP-4144436-A1 CURING CATALYST AND RESIN COMPOSITION Koei Chemical Company, Limited (JP) 2023-03-08 EP claimed
CN-115461147-A Curing catalyst and resin composition 广荣化学株式会社 2022-12-09 CN claimed
US-20190315892-A1 POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM SIRRUS, INC. 2019-10-17 US claimed
US-20170355789-A1 POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM SIRRUS, INC. 2017-12-14 US claimed
US-20170073438-A1 POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM SIRRUS, INC. 2017-03-16 US claimed
EP-2768872-A1 METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM Bioformix LLC (US) 2014-08-27 EP claimed
WO-2013066629-A1 METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM BIOFORMIX, LLC (US) 2013-05-10 WO claimed
US-12503439-B2 Heteroaryl compounds for the treatment of pain VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-12-23 US disclosed
EP-4630424-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS Third Harmonic Bio, Inc. (US) 2025-10-15 EP disclosed
US-20250304545-A1 WATER-SOLUBLE HETEROCYCLYL POLYMETHINE CHROMOPHORES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-10-02 US disclosed
US-12378200-B2 Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors ORSOBIO, INC. (US) 2025-08-05 US disclosed
CN-120058991-A Low ash content polypropylene resin and preparation method thereof 中国石油天然气股份有限公司 2025-05-30 CN disclosed
US-4146632-A NEMATOCIDES, ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed
US-4109006-A 1,4-DITHIINOXIDES WARREN-TEED LABORATORIES, INC. (US) 1978-08-22 US disclosed
US-4031130-A Aliphatic β-keto esters AGFA-GEVAERT, A.G. (DT) 1977-06-21 US disclosed
US-4029508-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1977-06-14 US disclosed
US-4026709-A Color photographic recording material CIBA-GEIGY AG (CH) 1977-05-31 US disclosed
US-3984432-A PHOSPHONIC ACID AND PHOSPHORIC ACID DERIVATIVES CIBA-GEIGY AG (CH) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378200-B2 Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors ALDH7A1, ACMSD, AMD1 GAA 214/4885MGAM 301/4885SI 637/4885
US-20250304545-A1 WATER-SOLUBLE HETEROCYCLYL POLYMETHINE CHROMOPHORES PWWP2B, WDR82, FOLR1 GAA 3146/4885MGAM 815/4885SI 804/4885
US-12503439-B2 Heteroaryl compounds for the treatment of pain TRPV1, SCN3A, KCNN3 GAA 932/4885MGAM 3800/4885SI 2901/4885
US-20170355789-A1 POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM BHMT2, BHMT, MACF1 GAA 2023/4885MGAM 64/4885SI 890/4885
US-20190315892-A1 POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM BHMT2, MACF1, BHMT GAA 2252/4885MGAM 89/4885SI 1281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.