Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.49 |
| ▸ | ABL1 | P00519 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9946848 | 1.00 | PTGES (0.49) | PTGESABL1MAPTTP53EPHX2 | |
| SCHEMBL9946597 | 0.94 | MAPT (0.48) | PTGESABL1MAPTTP53EPHX2 | |
| SCHEMBL9946826 | 0.90 | PTGES (0.51) | PTGESABL1MAPTTP53EPHX2 | |
| SCHEMBL9898228 | 0.87 | PTGES (0.48) | PTGESABL1MAPTTP53EPHX2 | |
| SCHEMBL9898230 | 0.87 | PTGES (0.48) | PTGESABL1MAPTTP53EPHX2 | |
| SCHEMBL9944979 | 0.87 | L3MBTL1 (0.41) | MAPT | |
| SCHEMBL9944977 | 0.87 | L3MBTL1 (0.41) | MAPT | |
| SCHEMBL9946856 | 0.85 | MAPT (0.53) | PTGESABL1MAPTEPHX2 | |
| SCHEMBL9946656 | 0.84 | PTGES (0.48) | PTGESABL1MAPTTP53EPHX2 | |
| SCHEMBL9945036 | 0.81 | ALDH1A1 (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | PTGES 3/4885ABL1 3956/4885MAPT 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.