Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9946693 | 1.00 | PTGES (0.46) | PTGESHTR4S100A4MAPK14ALDH1A1 | |
| SCHEMBL9944890 | 0.87 | CNR2 (0.43) | HTR4S100A4MAPK14CNR1CNR2 | |
| SCHEMBL10170842 | 0.82 | HPGD (0.42) | PTGESS100A4MAPK14POLBHPGD | |
| SCHEMBL11970141 | 0.82 | HPGD (0.42) | PTGESS100A4MAPK14POLBHPGD | |
| SCHEMBL9899306 | 0.80 | PTGES (0.46) | PTGESS100A4IRAK4HPGD | |
| SCHEMBL9899308 | 0.80 | PTGES (0.46) | PTGESS100A4IRAK4HPGD | |
| SCHEMBL9946585 | 0.80 | PTGES (0.53) | PTGESIRAK4 | |
| SCHEMBL9947006 | 0.80 | PTGES (0.53) | PTGESIRAK4 | |
| SCHEMBL9946720 | 0.76 | PTGES (0.44) | PTGESALDH1A1 | |
| SCHEMBL9947009 | 0.76 | PTGES (0.48) | PTGESS100A4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076673-A1 | 6-AMINO-2-PHENYLAMINO-1H-BENZIMIDAZOLE-5-CARBOXAMIDE- DERIVATIVES AND THEIR USE AS MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |