Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10313065 | 0.93 | FDPS (0.39) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28654242 | 0.91 | DNM1 (0.42) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL27421 | 0.91 | DNM1 (0.42) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6398037 | 0.90 | DNM1 (0.39) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9947119 | 0.88 | FDPS (0.37) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL19283464 | 0.87 | FDPS (0.39) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8432610 | 0.87 | FDPS (0.39) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL17243595 | 0.87 | CYP2D6 (0.30) | — | |
| SCHEMBL3620823 | 0.86 | FDPS (0.42) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3622828 | 0.84 | DNM1 (0.46) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410778-B1 | — | — | None | — | — | US | disclosed |
| US-8562966-B2 | End-modified poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-22 | — | — | US | disclosed |
| US-8562966-B2 | End-modified poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-22 | — | — | US | disclosed |
| US-20120149630-A1 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120149630-A1 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-06-14 | — | — | US | disclosed |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-10-02 | — | — | US | disclosed |
| WO-2008011561-A2 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-01-24 | — | — | WO | disclosed |
| CN-1101808-C | Preparation of organic diurethanes and/or polyurethanes and application thereof in preparation of di-and/or polyisocyanates | BASF AG (DE) | 2003-02-19 | — | — | CN | disclosed |
| US-6410778-B2 | REACTING ORGANIC DIAMINES OR POLYAMINES WITH UREA AND/OR ALKYL CARBAMATES, OR MIXTURE OF UREA, ALKYL CARBAMATE AND/OR DIALKYL CARBONATES, ALCOHOL IN PRESENCE OF A SOLUBLE ZIRCONIUM COMPOUND CATALYST; THERMAL DECOMPOSITION OF PRODUCT | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-25 | — | — | US | disclosed |
| US-20010005761-A1 | METHOD OF PRODUCING ORGANIC DIURETHANES AND/OR POLYURETHANES AND THEIR USE IN THE PRODUCTION OF DI-AND/OR POLYISOCYANATES | LAQUA GERHARD (DE) | 2001-06-28 | — | — | US | disclosed |
| CN-1201450-A | Method for producing organic diurethanes and/or polyurethanes and their use in production of di-and/or polyisocyanates | BASF AG (DE) | 1998-12-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010005761-A1 | METHOD OF PRODUCING ORGANIC DIURETHANES AND/OR POLYURETHANES AND THEIR USE IN THE PRODUCTION OF DI-AND/OR POLYISOCYANATES | UROD, AOC1, SAT1 | DNM1 3889/4885MEN1 3677/4885KMT2A 528/4885 |
| US-20120149630-A1 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF | PARN, PARG, POLL | DNM1 612/4885MEN1 2403/4885KMT2A 1064/4885 |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | PARN, PARG, POLL | DNM1 612/4885MEN1 2403/4885KMT2A 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.