Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216491 | 0.87 | OR51E2 (0.51) | OR51E2APLNRALDH1A1TSHRADRB2 | |
| SCHEMBL14608957 | 0.80 | ALDH1A1 (0.45) | APLNRALDH1A1HTTTSHRLMNA | |
| SCHEMBL5597294 | 0.79 | GAA (0.53) | OR51E2ALDH1A1HTTKMT2ACYP1A2 | |
| SCHEMBL2203559 | 0.79 | ALDH1A1 (0.56) | OR51E2APLNRALDH1A1HTTLMNA | |
| SCHEMBL31432473 | 0.77 | TRIM24 (0.56) | OR51E2ALDH1A1TSHRLMNAKMT2A | |
| SCHEMBL5223370 | 0.77 | ERN1 (0.56) | OR51E2ALDH1A1HTTLMNACYP1A2 | |
| SCHEMBL2095308 | 0.77 | OR51E2 (0.48) | OR51E2ALDH1A1HTTKMT2ACYP1A2 | |
| SCHEMBL20726018 | 0.77 | CYP1A2 (0.40) | ALDH1A1HTTLMNAKMT2ANPSR1 | |
| SCHEMBL11322262 | 0.75 | KMT2A (0.48) | OR51E2ALDH1A1TSHRLMNAKMT2A | |
| SCHEMBL1911389 | 0.75 | OR51E2 (0.46) | OR51E2ALDH1A1HTTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149686-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORKS (CA) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149686-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | MAP3K5, MAP3K6, MAP3K1 | OR51E2 4269/4885APLNR 3878/4885ALDH1A1 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.