Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014199 | 0.84 | GAA (0.44) | GAAGFERKDM4EL3MBTL1MAPT | |
| SCHEMBL9947695 | 0.72 | GAA (0.43) | GAAGFERKDM4EL3MBTL1MAPT | |
| SCHEMBL9947711 | 0.71 | KDM4E (0.54) | GAAGFERKDM4EL3MBTL1MAPT | |
| SCHEMBL2035472 | 0.67 | GAA (0.50) | GAAGFERKDM4EL3MBTL1MAPT | |
| SCHEMBL11454421 | 0.67 | NOTUM (0.53) | GAAGFERKDM4EL3MBTL1MAPT | |
| SCHEMBL9947824 | 0.67 | GAA (0.47) | GAAGFERKDM4EL3MBTL1MAPT | |
| SCHEMBL9948181 | 0.65 | GAA (0.48) | GAAGFERKDM4EL3MBTL1MAPT | |
| SCHEMBL9947652 | 0.64 | GAA (0.47) | GAAGFERKDM4EL3MBTL1MAPT | |
| SCHEMBL1717554 | 0.63 | NOTUM (0.52) | GAAGFERKDM4EL3MBTL1MAPT | |
| SCHEMBL11793628 | 0.62 | GAA (0.54) | GAAGFERKDM4EL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207347-B2 | Pyridone derivatives as NK3 antagonists | H. LUNDBECK A/S (DK) | 2012-06-26 | — | — | US | disclosed |