Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99481 | 0.90 | NPC1 (0.59) | RAB9ASMN1; SMN2NPC1TAAR1L3MBTL1 | |
| SCHEMBL100226 | 0.86 | RAB9A (0.52) | RAB9ASMN1; SMN2NPC1TAAR1L3MBTL1 | |
| SCHEMBL98541 | 0.80 | SMN1; SMN2 (0.43) | RAB9ASMN1; SMN2NPC1TAAR1L3MBTL1 | |
| SCHEMBL95051 | 0.76 | HDAC2 (0.73) | RAB9ASMN1; SMN2NPC1TAAR1L3MBTL1 | |
| SCHEMBL27559990 | 0.76 | FFAR1 (0.53) | RAB9AALDH1A1 | |
| SCHEMBL3905288 | 0.73 | ALDH1A1 (0.58) | RAB9ANPC1ALDH1A1HPGDMAPT | |
| SCHEMBL3035761 | 0.73 | ALDH1A1 (0.61) | RAB9ANPC1ALDH1A1HPGDMAPT | |
| SCHEMBL15822786 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL101169 | 0.73 | ALDH1A1 (0.53) | RAB9ASMN1; SMN2NPC1TAAR1ALDH1A1 | |
| SCHEMBL98747 | 0.73 | TDP1 (0.53) | RAB9ANPC1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | disclosed |