Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99480 | 0.90 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2L3MBTL1TAAR1 | |
| SCHEMBL100226 | 0.87 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1TAAR1 | |
| SCHEMBL98541 | 0.79 | SMN1; SMN2 (0.43) | NPC1RAB9ASMN1; SMN2L3MBTL1TAAR1 | |
| SCHEMBL5969191 | 0.75 | RAB9A (0.88) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16900376 | 0.75 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2TAAR1LMNA | |
| SCHEMBL27559990 | 0.75 | FFAR1 (0.53) | RAB9AALDH1A1 | |
| SCHEMBL19246213 | 0.74 | ALDH1A1 (0.72) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL14469162 | 0.74 | NPC1 (0.84) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL3240913 | 0.74 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3905288 | 0.73 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | disclosed |