Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 4/20 | 0.42 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948891 | 1.00 | AR (0.43) | ARNR3C2PGRMBOAT4CYP19A1 | |
| SCHEMBL3357144 | 0.79 | CYP19A1 (0.44) | MBOAT4CYP19A1STS | |
| SCHEMBL3354601 | 0.70 | AR (0.38) | ARNR3C2PGRMBOAT4CYP19A1 | |
| SCHEMBL11795958 | 0.68 | AR (0.64) | ARNR3C2PGRCYP19A1 | |
| SCHEMBL9948618 | 0.67 | PGR (0.41) | ARNR3C2PGRMBOAT4CYP19A1 | |
| SCHEMBL11798667 | 0.66 | CYP19A1 (0.47) | PGRMBOAT4CYP19A1 | |
| SCHEMBL6387112 | 0.66 | AR (0.44) | ARNR3C2PGRMBOAT4CYP19A1 | |
| SCHEMBL6244949 | 0.66 | AR (0.49) | ARNR3C2PGRMBOAT4CYP19A1 | |
| SCHEMBL6535044 | 0.66 | AR (0.70) | ARCYP19A1 | |
| SCHEMBL13372823 | 0.65 | AR (0.59) | ARNR3C2PGRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207150-B2 | 17β-cyano-19-nor-androst-4-ene derivative, its use and medicaments comprising the derivative | Bayer Pharma AG (DE) | 2012-06-26 | — | — | US | disclosed |