Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | IRS1 | P35568 | 1/20 | 0.37 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1364647 | 0.88 | GPR35 (0.49) | GPR35L3MBTL1PLA2G4AAKT1IRS1 | |
| SCHEMBL1157118 | 0.88 | GPR35 (0.49) | GPR35L3MBTL1PLA2G4AAKT1IRS1 | |
| SCHEMBL1157064 | 0.88 | GPR35 (0.49) | GPR35L3MBTL1PLA2G4AAKT1IRS1 | |
| SCHEMBL1365121 | 0.88 | GPR35 (0.49) | GPR35L3MBTL1PLA2G4AAKT1IRS1 | |
| SCHEMBL13961926 | 0.88 | GPR35 (0.65) | GPR35L3MBTL1KDM4EPLA2G4AAKT1 | |
| SCHEMBL9948994 | 0.86 | GPR35 (0.66) | GPR35 | |
| SCHEMBL18558705 | 0.82 | GPR35 (0.58) | GPR35L3MBTL1KDM4EPLA2G4AAKT1 | |
| SCHEMBL12704404 | 0.81 | GPR35 (0.56) | GPR35L3MBTL1KDM4ENOD2PLA2G4A | |
| SCHEMBL12374321 | 0.81 | GPR35 (0.74) | GPR35L3MBTL1KDM4EPLA2G4AAKT1 | |
| SCHEMBL1593215 | 0.81 | GPR35 (0.74) | GPR35L3MBTL1KDM4EPLA2G4AAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9166167-B2 | P-type materials and organic electronic devices | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-10-20 | — | — | US | disclosed |
| US-20120161117-A1 | P-TYPE MATERIALS AND ORGANIC ELECTRONIC DEVICES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120161117-A1 | P-TYPE MATERIALS AND ORGANIC ELECTRONIC DEVICES | POP1, CACNA1A, PNN | GPR35 4807/4885L3MBTL1 3158/4885KDM4E 3679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.