Dimethylamine

Dimethylamine

SCHEMBL9949305

CCC[Si](C)(C)OCCN(C)C.CNC

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.30
PRMT3 O60678 1/20 0.30
CARM1 Q86X55 1/20 0.30
PRMT6 Q96LA8 1/20 0.30
PRMT1 Q99873 1/20 0.30
PRMT8 Q9NR22 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16313646 0.94 DNM1 (0.32) DNM1
SCHEMBL9949907 0.92
SCHEMBL9948805 0.89
SCHEMBL9949561 0.89
SCHEMBL9949374 0.85
Dimethylamine SCHEMBL9950230 0.84 DNM1 (0.30) DNM1PRMT3CARM1PRMT6PRMT1
Dimethylamine SCHEMBL16492426 0.82 PRMT3 (0.31) DNM1PRMT3CARM1PRMT6PRMT1
SCHEMBL9949294 0.77
SCHEMBL16492341 0.77
SCHEMBL9949302 0.77 ALDH1A1 (0.38) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962745-B2 Functionalized polymers and vulcanizates with reduced hysteretic loss BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
US-20120165464-A1 FUNCTIONALIZED POLYMERS AND VULCANIZATES WITH REDUCED HYSTERETIC LOSS BRIDGESTONE CORPORATION (JP) 2012-06-28 US claimed
US-8962745-B2 Functionalized polymers and vulcanizates with reduced hysteretic loss BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
US-20120165464-A1 FUNCTIONALIZED POLYMERS AND VULCANIZATES WITH REDUCED HYSTERETIC LOSS BRIDGESTONE CORPORATION (JP) 2012-06-28 US disclosed